OBJECTIVE: We investigated whether persons with self-reported chemical sensitivity (CS) have an attention bias and enhanced sensitization to chemical exposure. METHODS: Chemosomatosensory, olfactory, and auditory event-related potentials (ERPs) were recorded from 21 CS subjects and 17 controls in attend and ignore conditions. Reaction times (RTs) and magnitude estimations of perceived intensity were collected in the attend condition. ERPs were averaged over attention conditions and during the first/second part of the testing. RESULTS: ERP patterns indicated that CS subjects did not habituate to the same extent as the controls and had difficulties ignoring the chemical exposure. CS subjects had faster overall RT, and the perceived intensities for the chemosomatosensory stimuli did not decrease with time in the CS group, which was the case for the controls. CONCLUSIONS: These results indicating attention bias and enhanced sensitization in CS suggest alterations in central, cognitive responses to chemical exposure.
OBJECTIVE: We investigated whether persons with self-reported chemical sensitivity (CS) have an attention bias and enhanced sensitization to chemical exposure. METHODS: Chemosomatosensory, olfactory, and auditory event-related potentials (ERPs) were recorded from 21 CS subjects and 17 controls in attend and ignore conditions. Reaction times (RTs) and magnitude estimations of perceived intensity were collected in the attend condition. ERPs were averaged over attention conditions and during the first/second part of the testing. RESULTS: ERP patterns indicated that CS subjects did not habituate to the same extent as the controls and had difficulties ignoring the chemical exposure. CS subjects had faster overall RT, and the perceived intensities for the chemosomatosensory stimuli did not decrease with time in the CS group, which was the case for the controls. CONCLUSIONS: These results indicating attention bias and enhanced sensitization in CS suggest alterations in central, cognitive responses to chemical exposure.
Authors: Sine Skovbjerg; Robert Zachariae; Alice Rasmussen; Jeanne Duus Johansen; Jesper Elberling Journal: Environ Health Prev Med Date: 2009-12-02 Impact factor: 3.674
Authors: Linus Andersson; Anna-Sara Claeson; Thomas Meinertz Dantoft; Sine Skovbjerg; Nina Lind; Steven Nordin Journal: Int Arch Occup Environ Health Date: 2015-04-28 Impact factor: 3.015
Authors: Sine Skovbjerg; Alice Rasmussen; Robert Zachariae; Lone Schmidt; Rikke Lund; Jesper Elberling Journal: Environ Health Prev Med Date: 2011-03-01 Impact factor: 3.674
Authors: Marlene Pacharra; Stefan Kleinbeck; Michael Schäper; Meinolf Blaszkewicz; Christoph van Thriel Journal: Int Arch Occup Environ Health Date: 2016-04-28 Impact factor: 3.015