Literature DB >> 19379604

Deleterious effect of smoking and nasal septal deviation on mucociliary clearance and improvement after septoplasty.

Murat Karaman1, Arman Tek.   

Abstract

OBJECTIVES: To investigate the effect of septal deviation, septoplasty, and smoking upon nasal mucociliary clearance by using saccharine test.
METHODS: Included in this study were 40 patients (15 women and 25 men) who had septal deviation and septoplasty surgery performed between March and June 2006. Patients are classified into three groups: group I (n = 20) nonsmoking patients who had septoplasty surgery, group II (n = 20) smoking patients who had septoplasty surgery, and the control (n = 20) group. None of the control group has nasal breathing problem or smoking history. For determining preoperative and postoperative nasal mucociliary clearance (MCC) time, a saccharine test was performed on the patients 1 day before surgery and at the third month of postoperative control.
RESULTS: Preoperative and postoperative nasal MCC time in patients of group I are statistically significantly lower than the group II (p < 0.01). Postoperative MCC time in group I and II is significantly decreased compared with preoperative MCC time, statistically (p < 0.01). Preoperative and postoperative MCC time of group I and group II is significantly higher than MCC time of the control group (p < 0.01).
CONCLUSION: Nasal septal deviation and smoking deteriorates nasal MCC time and this result can be shown easily with the saccharine test. Properly performed septoplasty surgery decreases nasal MCC time during the late postoperative period but MCC times are still longer than normal. The saccharine test can be used for following up the effect of septoplasty upon nasal mucosa.

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Year:  2009        PMID: 19379604     DOI: 10.2500/ajra.2009.23.3253

Source DB:  PubMed          Journal:  Am J Rhinol Allergy        ISSN: 1945-8932            Impact factor:   2.467


  9 in total

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4.  A prediction modeling based on SNOT-22 score for endoscopic nasal septoplasty: a retrospective study.

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6.  Environmental Risk Factors in Patients with Noninvasive Fungal Sinusitis.

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7.  The effects of smoking and smoking cessation on nasal mucociliary clearance, mucus properties and inflammation.

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8.  Evaluation of Nasal Mucociliary Clearance Time in COVID-19 Patients.

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Review 9.  Effects of cigarette smoking on the respiratory epithelium and its role in the pathogenesis of chronic rhinosinusitis.

Authors:  Edwin Tamashiro; Noam A Cohen; James N Palmer; Wilma Terezinha Anselmo Lima
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  9 in total

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