Literature DB >> 1937832

Cytokine regulation of murine leishmaniasis: interleukin 4 is not sufficient to mediate progressive disease in resistant C57BL/6 mice.

M D Sadick1, N Street, T R Mosmann, R M Locksley.   

Abstract

Neutralization of interleukin 4 (IL-4) at the time of infection with Leishmania major allowed susceptible BALB/c mice to heal. Recombinant IL-4, however, had little effect on the course of L. major infection in resistant C57BL/6 mice, nor did coinfection with Nippostrongylus brasiliensis, despite marked elevation of endogenous IL-4 levels.

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Year:  1991        PMID： 1937832      PMCID： PMC259104          DOI： 10.1128/iai.59.12.4710-4714.1991

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  30 in total

1.  IL-4 inhibits the synthesis of IFN-gamma and induces the synthesis of IgE in human mixed lymphocyte cultures.

Authors:  D Vercelli; H H Jabara; R P Lauener; R S Geha
Journal:  J Immunol       Date:  1990-01-15       Impact factor: 5.422

2.  Mast cell lines produce lymphokines in response to cross-linkage of Fc epsilon RI or to calcium ionophores.

Authors:  M Plaut; J H Pierce; C J Watson; J Hanley-Hyde; R P Nordan; W E Paul
Journal:  Nature       Date:  1989-05-04       Impact factor: 49.962

3.  Antibody to interleukin-5 inhibits helminth-induced eosinophilia in mice.

Authors:  R L Coffman; B W Seymour; S Hudak; J Jackson; D Rennick
Journal:  Science       Date:  1989-07-21       Impact factor: 47.728

4.  Nippostrongylus brasiliensis in young rats. Lymphocytes expel larval infections but not adult worms.

Authors:  R J Love; B M Ogilvie
Journal:  Clin Exp Immunol       Date:  1975-07       Impact factor: 4.330

5.  IL-4 inhibits H2O2 production and antileishmanial capacity of human cultured monocytes mediated by IFN-gamma.

Authors:  M Lehn; W Y Weiser; S Engelhorn; S Gillis; H G Remold
Journal:  J Immunol       Date:  1989-11-01       Impact factor: 5.422

6.  Administration of monoclonal anti-IFN-gamma antibodies in vivo abrogates natural resistance of C3H/HeN mice to infection with Leishmania major.

Authors:  M Belosevic; D S Finbloom; P H Van Der Meide; M V Slayter; C A Nacy
Journal:  J Immunol       Date:  1989-07-01       Impact factor: 5.422

7.  Phenotypic and functional analysis of murine CD3+,CD4-,CD8- TCR-gamma delta-expressing peripheral T cells.

Authors:  R Q Cron; T F Gajewski; S O Sharrow; F W Fitch; L A Matis; J A Bluestone
Journal:  J Immunol       Date:  1989-06-01       Impact factor: 5.422

8.  The IgE and IgG subclass responses of mice to four helminth parasites.

Authors:  S G Zakroff; L Beck; E G Platzer; H L Spiegelberg
Journal:  Cell Immunol       Date:  1989-03       Impact factor: 4.868

9.  Recombinant interleukin 4 suppresses the production of interferon gamma by human mononuclear cells.

Authors:  R Peleman; J Wu; C Fargeas; G Delespesse
Journal:  J Exp Med       Date:  1989-11-01       Impact factor: 14.307

10.  Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

Authors:  F P Heinzel; M D Sadick; B J Holaday; R L Coffman; R M Locksley
Journal:  J Exp Med       Date:  1989-01-01       Impact factor: 14.307
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  16 in total

Review 1.  Cardiac myosin and the TH1/TH2 paradigm in autoimmune myocarditis.

Authors:  M W Cunningham
Journal:  Am J Pathol       Date:  2001-07       Impact factor: 4.307

2.  Interleukin-12 is capable of generating an antigen-specific Th1-type response in the presence of an ongoing infection-driven Th2-type response.

Authors:  L R Schopf; J L Bliss; L M Lavigne; C L Chung; S F Wolf; J P Sypek
Journal:  Infect Immun       Date:  1999-05       Impact factor: 3.441

3.  Coinfection with Toxoplasma gondii inhibits antigen-specific Th2 immune responses, tissue inflammation, and parasitism in BALB/c mice infected with Leishmania major.

Authors:  H C Santiago; M A Oliveira; E A Bambirra; A M Faria; L C Afonso; L Q Vieira; R T Gazzinelli
Journal:  Infect Immun       Date:  1999-09       Impact factor: 3.441

4.  Low-dose UVB contributes to host resistance against Leishmania amazonensis infection in mice through induction of gamma interferon and tumor necrosis factor alpha cytokines.

Authors:  Noor Mohammad Khaskhely; Motoyoshi Maruno; Hiroshi Uezato; Atsushi Takamiyagi; Saeef Taher Ramzi; Khan Mohammad Al-Kasem; Ken-ichi Kariya; Takayoshi Toda; Yoshihisa Hashiguchi; Eduardo A Gomez Landires; Shigeo Nonaka
Journal:  Clin Diagn Lab Immunol       Date:  2002-05

5.  Administration of plasmids expressing interleukin-4 and interleukin-10 causes BALB/c mice to induce a T helper 2-type response despite the expected T helper 1-type response with a low-dose infection of Leishmania major.

Authors:  Kazuo Yamakami; Shinkichi Akao; Takushi Tadakuma; Yoshio Nitta; Jyun-Ichi Miyazaki; Nobuyuki Yoshizawa
Journal:  Immunology       Date:  2002-04       Impact factor: 7.397

6.  Progression of visceral leishmaniasis due to Leishmania infantum in BALB/c mice is markedly slowed by prior infection with Trichinella spiralis.

Authors:  D Rousseau; Y Le Fichoux; X Stien; I Suffia; B Ferrua; J Kubar
Journal:  Infect Immun       Date:  1997-12       Impact factor: 3.441

7.  Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses.

Authors:  G S Nabors; J P Farrell
Journal:  Infect Immun       Date:  1994-12       Impact factor: 3.441

8.  Th1 and Th2 cell-associated cytokines in experimental visceral leishmaniasis.

Authors:  G D Miralles; M Y Stoeckle; D F McDermott; F D Finkelman; H W Murray
Journal:  Infect Immun       Date:  1994-03       Impact factor: 3.441

9.  Does T Helper Differentiation Correlate with Resistance or Susceptibility to Infection with L. major? Some Insights From the Murine Model.

Authors:  Fabienne Tacchini-Cottier; Tiffany Weinkopff; Pascal Launois
Journal:  Front Immunol       Date:  2012-02-27       Impact factor: 7.561

10.  Leishmania major-specific, CD4+, major histocompatibility complex class II-restricted T cells derived in vitro from lymphoid tissues of naive mice.

Authors:  A H Shankar; R G Titus
Journal:  J Exp Med       Date:  1993-07-01       Impact factor: 14.307
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