Literature DB >> 19372015

Mechanism of androgen receptor action.

Jin Li1, Farook Al-Azzawi.   

Abstract

Recent research provides a much more detailed understanding of the role of the androgen receptor in normal human development and physiology, its structure, and its functioning. This review discusses genomic and non-genomic actions of the androgen receptor, as well as their co-regulators. We also explore several clinically relevant aspects of the molecular biology of the androgen receptor and its co-regulators.

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Year:  2009        PMID: 19372015     DOI: 10.1016/j.maturitas.2009.03.008

Source DB:  PubMed          Journal:  Maturitas        ISSN: 0378-5122            Impact factor:   4.342


  33 in total

1.  Androgens enhance the glycolytic metabolism and lactate export in prostate cancer cells by modulating the expression of GLUT1, GLUT3, PFK, LDH and MCT4 genes.

Authors:  Cátia V Vaz; Ricardo Marques; Marco G Alves; Pedro F Oliveira; José E Cavaco; Cláudio J Maia; Sílvia Socorro
Journal:  J Cancer Res Clin Oncol       Date:  2015-06-06       Impact factor: 4.553

2.  Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men.

Authors:  Matthew S Panizzon; Richard L Hauger; Lindon J Eaves; Chi-Hua Chen; Anders M Dale; Lisa T Eyler; Bruce Fischl; Christine Fennema-Notestine; Carol E Franz; Michael D Grant; Kristen C Jacobson; Amy J Jak; Michael J Lyons; Sally P Mendoza; Michael C Neale; Elizabeth Prom-Wormley; Larry J Seidman; Ming T Tsuang; Hong Xian; William S Kremen
Journal:  Neuroimage       Date:  2011-10-01       Impact factor: 6.556

3.  Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology.

Authors:  Azriel Schmidt; Donald B Kimmel; Chang Bai; Angela Scafonas; Sujane Rutledge; Robert L Vogel; Sheila McElwee-Witmer; Fang Chen; Pascale V Nantermet; Viera Kasparcova; Chih-Tai Leu; Hai-Zhuan Zhang; Mark E Duggan; Michael A Gentile; Paul Hodor; Brenda Pennypacker; Patricia Masarachia; Evan E Opas; Sharon A Adamski; Tara E Cusick; Jiabing Wang; Helen J Mitchell; Yuntae Kim; Thomayant Prueksaritanont; James J Perkins; Robert S Meissner; George D Hartman; Leonard P Freedman; Shun-ichi Harada; William J Ray
Journal:  J Biol Chem       Date:  2010-03-31       Impact factor: 5.157

4.  Short poly-glutamine repeat in the androgen receptor in New World monkeys.

Authors:  Chihiro Hiramatsu; Annika Paukner; Hika Kuroshima; Kazuo Fujita; Stephen J Suomi; Miho Inoue-Murayama
Journal:  Meta Gene       Date:  2017-09-01

5.  Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy.

Authors:  Elgene Lim; Min Ni; Shiliang Cao; Aditi Hazra; Rulla M Tamimi; Myles Brown
Journal:  Curr Breast Cancer Rep       Date:  2014-06-01

6.  Effect of 3α-anderostanediol and indomethacin on acquisition, consolidation and retrieval stage of spatial memory in adult male rats.

Authors:  Somayeh Assadian Narenji; Nasser Naghdi; Shahrbano Oryan; Kayhan Azadmanesh
Journal:  Iran Biomed J       Date:  2012

7.  Isotretinoin and FoxO1: A scientific hypothesis.

Authors:  Bodo C Melnik
Journal:  Dermatoendocrinol       Date:  2011-07-01

8.  Testosterone therapy for reduced libido in women.

Authors:  Rosemary Basson
Journal:  Ther Adv Endocrinol Metab       Date:  2010-08       Impact factor: 3.565

Review 9.  Sex differences in stroke.

Authors:  Roy A M Haast; Deborah R Gustafson; Amanda J Kiliaan
Journal:  J Cereb Blood Flow Metab       Date:  2012-10-03       Impact factor: 6.200

10.  5α-Dihydrotestosterone regulates the expression of L-type calcium channels and calcium-binding protein regucalcin in human breast cancer cells with suppression of cell growth.

Authors:  Ricardo Marques; Carina G Peres; Cátia V Vaz; Inês M Gomes; Marília I Figueira; Elisa Cairrão; Ignacio Verde; Cláudio J Maia; Sílvia Socorro
Journal:  Med Oncol       Date:  2015-08-09       Impact factor: 3.064

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