| Literature DB >> 193712 |
K M Kutty, R Redheendran, D Murphy.
Abstract
Human serum beta-lipoproteins, isolated by percipitation with heparin-calcium mixture, showed cholinesterase activity. The enzyme activity was almost proportional to the lipoprotein concentration. Rats, treated with neostigmine, a cholinesterase inhibitor, showed a significant decrease in serum beta-lipoprotein and in the incorporation of H3-lysine into the lipoprotein compared to untreated controls. The decreased incorporation of H3-lysine into beta-lipoprotein was associated with increased labelling of alpha-lopoprotein. There was no significant difference in the labelling of pre-beta-lipoprotein. We propose that LDL is formed from VLDL in the presence of cholinesterase.Entities:
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Year: 1977 PMID: 193712 DOI: 10.1007/bf01922187
Source DB: PubMed Journal: Experientia ISSN: 0014-4754