Literature DB >> 19370690

Honey and lozenges for children with non-specific cough.

Selamawit Mulholland1, Anne B Chang.   

Abstract

BACKGROUND: Chronic non-specific cough is a chronic, dry cough of in the absence of identifiable respiratory disease or known aetiology. Although it is usually not reflective of an underlying severe illness, it does cause significant morbidity, and as such relief from it is often sought. The use of honey and lozenges to soothe upper respiratory tract irritation is common, inexpensive, and potentially more effective in treating the symptoms than pharmacological interventions.
OBJECTIVES: To evaluate the efficacy of honey and/or lozenges in the management of children with chronic non-specific cough. SEARCH STRATEGY: The Cochrane Airways Group searched the Cochrane Register of Controlled Trials (CENTRAL), MEDLINE, OLDMEDLINE, and EMBASE databases in October 2008. SELECTION CRITERIA: All randomised controlled trials comparing honey or lozenges with a placebo in treating children with chronic non-specific cough. DATA COLLECTION AND ANALYSIS: The results of the searches were assessed according to the pre-determined criteria. None of the trials identified by the searches were eligible for inclusion, leaving no data available for analysis in this review. MAIN
RESULTS: The search did not provide any applicable randomised controlled trials that investigated the efficacy of honey and lozenges in treating children with non-specific chronic cough. Data from acute studies suggest a potential role for honey in relieving cough, but whether this is applicable to chronic cough is unknown. AUTHORS'
CONCLUSIONS: Clinically, this review was unable to provide any justifiable recommendation for or against honey and/or lozenges due to the lack of evidence. The absence of applicable studies highlights the need for further research into the area of treating children with chronic non-specific coughs with honey and/or lozenges. These treatments are not recommended when managing very young children (as lozenges are a potential choking hazard, and honey may cause infant botulism in children under 1 year of age).

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Year:  2009        PMID: 19370690      PMCID: PMC7202236          DOI: 10.1002/14651858.CD007523.pub2

Source DB:  PubMed          Journal:  Cochrane Database Syst Rev        ISSN: 1361-6137


  31 in total

Review 1.  The powerful placebo in cough studies?

Authors:  R Eccles
Journal:  Pulm Pharmacol Ther       Date:  2002       Impact factor: 3.410

2.  Efficacy of a single evening dose of syrup containing paracetamol, dextromethorphan hydrobromide, doxylamine succinate and ephedrine sulfate in subjects with multiple common cold symptoms.

Authors:  H Mizoguchi; A Wilson; G R Jerdack; J D Hull; M Goodale; J M Grender; B A Tyler
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3.  [Does the inhalation of a 1% L-menthol solution in the premedication of fiberoptic bronchoscopy affect coughing and the sensation of dyspnea?].

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Journal:  Pneumologie       Date:  2001-03

Review 4.  Guidelines for evaluating chronic cough in pediatrics: ACCP evidence-based clinical practice guidelines.

Authors:  Anne B Chang; William B Glomb
Journal:  Chest       Date:  2006-01       Impact factor: 9.410

5.  The antitussive effect of dextromethorphan in relation to CYP2D6 activity.

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Journal:  Br J Clin Pharmacol       Date:  1999-09       Impact factor: 4.335

6.  Dextromethorphan and codeine: objective assessment of antitussive activity in patients with chronic cough.

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Journal:  J Int Med Res       Date:  1983       Impact factor: 1.671

7.  Effect of dextromethorphan, diphenhydramine, and placebo on nocturnal cough and sleep quality for coughing children and their parents.

Authors:  Ian M Paul; Katharine E Yoder; Kathryn R Crowell; Michele L Shaffer; Heidi S McMillan; Lisa C Carlson; Deborah A Dilworth; Cheston M Berlin
Journal:  Pediatrics       Date:  2004-07       Impact factor: 7.124

8.  What is the burden of chronic cough for families?

Authors:  Julie M Marchant; Peter A Newcombe; Elizabeth F Juniper; Jeannie K Sheffield; Stephen L Stathis; Anne B Chang
Journal:  Chest       Date:  2008-07-18       Impact factor: 9.410

9.  Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents.

Authors:  Ian M Paul; Jessica Beiler; Amyee McMonagle; Michele L Shaffer; Laura Duda; Cheston M Berlin
Journal:  Arch Pediatr Adolesc Med       Date:  2007-12

10.  Development of a parent-proxy quality-of-life chronic cough-specific questionnaire: clinical impact vs psychometric evaluations.

Authors:  Peter A Newcombe; Jeanie K Sheffield; Elizabeth F Juniper; Julie M Marchant; Ria A Halsted; I Brent Masters; Anne B Chang
Journal:  Chest       Date:  2008-02       Impact factor: 9.410

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Authors:  Hywel Evans; Catherine Tuleu; Alastair Sutcliffe
Journal:  J R Soc Med       Date:  2010-05       Impact factor: 5.344

2.  [Consensus statement on the evaluation and therapy of chronic cough in children].

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Journal:  Wien Klin Wochenschr       Date:  2014-06-12       Impact factor: 1.704

Review 3.  Analysis of the Literature on Chronic Cough in Children.

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Journal:  Open Respir Med J       Date:  2017-04-27

4.  Prolonged Cough in Pediatric Population First Line Care, Belgian Guidelines.

Authors:  Sophie Leconte; Stéphanie Valentin; Estelle Dromelet; Michel De Jonghe
Journal:  Open Respir Med J       Date:  2017-08-21

Review 5.  Honey for acute cough in children.

Authors:  Olabisi Oduwole; Ekong E Udoh; Angela Oyo-Ita; Martin M Meremikwu
Journal:  Cochrane Database Syst Rev       Date:  2018-04-10

Review 6.  Potentials of Antitussive Traditional Persian Functional Foods for COVID-19 Therapy.

Authors:  Ghazaleh Mosleh; Parmis Badr; Meysam Zaeri; Abdolali Mohagheghzadeh
Journal:  Front Pharmacol       Date:  2021-07-16       Impact factor: 5.810

  6 in total

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