Literature DB >> 19364093

Synthesis of isoxazolo[5,4-b]pyridines by microwave-assisted multi-component reactions in water.

Shu-Jiang Tu1, Xiao-Hong Zhang, Zheng-Guo Han, Xu-Dong Cao, Shan-Shan Wu, Shu Yan, Wen-Juan Hao, Ge Zhang, Ning Ma.   

Abstract

A series of new polycyclic-fused isoxazolo[5,4-b]pyridines were obtained by a one-pot tandem reaction under microwave irradiation in water. Without any use of additional reagent or catalyst, the synthetic protocol represents a green one and makes this methodology suitable for library synthesis in drug discovery efforts.

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Year:  2009        PMID: 19364093     DOI: 10.1021/cc800212v

Source DB:  PubMed          Journal:  J Comb Chem        ISSN: 1520-4766


  6 in total

1.  A green synthetic approach toward the synthesis of structurally diverse spirooxindole derivative libraries under catalyst-free conditions.

Authors:  Nazia Kausar; Abdulla Al Masum; Md Maidul Islam; Asish R Das
Journal:  Mol Divers       Date:  2017-02-11       Impact factor: 2.943

2.  Microwave-assisted multicomponent reaction in water leading to highly regioselective formation of benzo[f]azulen-1-ones.

Authors:  Shu-Liang Wang; Chuang Cheng; Fei-Yue Wu; Bo Jiang; Feng Shi; Shu-Jiang Tu; Trideep Rajale; Guigen Li
Journal:  Tetrahedron       Date:  2011-06-24       Impact factor: 2.457

Review 3.  Synthetic and application perspectives of azapodophyllotoxins: alternative scaffolds of podophyllotoxin.

Authors:  A Kumar; V Kumar; A E Alegria; S V Malhotra
Journal:  Curr Med Chem       Date:  2011       Impact factor: 4.530

4.  1-(3-p-Tolyl-isoxazol-5-yl)cyclo-hexa-nol.

Authors:  Ouafaa Khalil; Khalid Bougrin; Rachid Benhida; Mohamed Soufiaoui; Lahcen El Ammari
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-11-04

Review 5.  Diversity oriented syntheses of conventional heterocycles by smart multi component reactions (MCRs) of the last decade.

Authors:  Heiner Eckert
Journal:  Molecules       Date:  2012-01-20       Impact factor: 4.411

Review 6.  Microwave multicomponent synthesis.

Authors:  Helmut M Hügel
Journal:  Molecules       Date:  2009-12-01       Impact factor: 4.411

  6 in total

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