Literature DB >> 19362885

Early identification and treatment of Alzheimer's disease: social and fiscal outcomes.

David L Weimer1, Mark A Sager.   

Abstract

BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disease that places substantial burdens on those who provide support for family members with declining cognitive and functional abilities. Many AD patients eventually require formal long-term care services because of the absence, exhaustion, or inability of family members to provide care. The costs of long-term care, and especially nursing home care, often deplete private financial resources, placing a substantial burden on state Medicaid programs. Current evidence suggests that pharmacological treatments and caregiver interventions can delay entry into nursing homes and potentially reduce Medicaid costs. However, these cost savings are not being realized because many patients with AD are either not diagnosed or diagnosed at late stages of the disease, and have no access to Medicare-funded caregiver support programs. METHODS AND
RESULTS: A Monte Carlo cost-benefit analysis, based on estimates of parameters available in the medical literature, suggests that the early identification and treatment of AD have the potential to result in large, positive net social benefits as well as positive net savings for states and the federal government.
CONCLUSIONS: These findings indicate that the early diagnosis and treatment of AD are not only socially desirable in terms of increasing economic efficiency, but also fiscally attractive from both state and federal perspectives. These findings also suggest that failure to fund effective caregiver interventions may be fiscally unsound.

Entities:  

Mesh:

Year:  2009        PMID: 19362885      PMCID: PMC2785909          DOI: 10.1016/j.jalz.2009.01.028

Source DB:  PubMed          Journal:  Alzheimers Dement        ISSN: 1552-5260            Impact factor:   21.566


  37 in total

1.  Survival following dementia onset: Alzheimer's disease and vascular dementia.

Authors:  Annette L Fitzpatrick; Lewis H Kuller; Oscar L Lopez; Claudia H Kawas; William Jagust
Journal:  J Neurol Sci       Date:  2004-12-23       Impact factor: 3.181

2.  Is donepezil therapy associated with reduced mortality in nursing home residents with dementia?

Authors:  Mason C Gasper; Brian R Ott; Kate L Lapane
Journal:  Am J Geriatr Pharmacother       Date:  2005-03

3.  The effect of a memory screening program on the early diagnosis of Alzheimer disease.

Authors:  Warren W Barker; Cheryl Luis; Dylan Harwood; David Loewenstein; Marina Bravo; Ray Ownby; Ranjan Duara
Journal:  Alzheimer Dis Assoc Disord       Date:  2005 Jan-Mar       Impact factor: 2.703

4.  How much do persons with Alzheimer's disease cost Medicare?

Authors:  D H Taylor; F A Sloan
Journal:  J Am Geriatr Soc       Date:  2000-06       Impact factor: 5.562

5.  Improving caregiver well-being delays nursing home placement of patients with Alzheimer disease.

Authors:  Mary S Mittelman; William E Haley; Olivio J Clay; David L Roth
Journal:  Neurology       Date:  2006-11-14       Impact factor: 9.910

6.  Do cholinergic therapies have disease-modifying effects in Alzheimer's disease?

Authors:  Marwan N Sabbagh; Martin R Farlow; Normal Relkin; Thomas G Beach
Journal:  Alzheimers Dement       Date:  2006-04       Impact factor: 21.566

7.  Patient and caregiver characteristics associated with depression in caregivers of patients with dementia.

Authors:  Kenneth E Covinsky; Robert Newcomer; Patrick Fox; Joan Wood; Laura Sands; Kyle Dane; Kristine Yaffe
Journal:  J Gen Intern Med       Date:  2003-12       Impact factor: 5.128

Review 8.  Disease-modifying therapies in Alzheimer's disease.

Authors:  Stephen Salloway; Jacobo Mintzer; Myron F Weiner; Jeffrey L Cummings
Journal:  Alzheimers Dement       Date:  2008-02-20       Impact factor: 21.566

9.  Reaction to a dementia diagnosis in individuals with Alzheimer's disease and mild cognitive impairment.

Authors:  Brian D Carpenter; Chengjie Xiong; Emily K Porensky; Monica M Lee; Patrick J Brown; Mary Coats; David Johnson; John C Morris
Journal:  J Am Geriatr Soc       Date:  2008-01-05       Impact factor: 5.562

10.  Dementia assessment in primary care: results from a study in three managed care systems.

Authors:  Linda Boise; Margaret B Neal; Jeffrey Kaye
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2004-06       Impact factor: 6.053

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  55 in total

1.  Dementia: commissioning for quality.

Authors:  Nick Cartmell
Journal:  Br J Gen Pract       Date:  2012-02       Impact factor: 5.386

2.  The art of sharing the diagnosis and management of Alzheimer's disease with patients and caregivers: recommendations of an expert consensus panel.

Authors:  George T Grossberg; Daniel D Christensen; Patrick A Griffith; Diana R Kerwin; Gail Hunt; Eric J Hall
Journal:  Prim Care Companion J Clin Psychiatry       Date:  2010

3.  [New possibilities for automated diagnosis of dementia].

Authors:  S Klöppel
Journal:  Nervenarzt       Date:  2010-12       Impact factor: 1.214

4.  Four sensitive screening tools to detect cognitive dysfunction in geriatric emergency department patients: brief Alzheimer's Screen, Short Blessed Test, Ottawa 3DY, and the caregiver-completed AD8.

Authors:  Christopher R Carpenter; Elizabeth R Bassett; Grant M Fischer; Jonathan Shirshekan; James E Galvin; John C Morris
Journal:  Acad Emerg Med       Date:  2011-04       Impact factor: 3.451

Review 5.  Building capacity for dementia care: training program to develop primary care memory clinics.

Authors:  Linda Lee; M Janet Kasperski; W Wayne Weston
Journal:  Can Fam Physician       Date:  2011-07       Impact factor: 3.275

6.  Routine cognitive screening in a neurology practice: Effect on physician behavior.

Authors:  Michael Rosenbloom; Soo Borson; Terry Barclay; Leah R Hanson; Ann Werner; Logan Stuck; John McCarten
Journal:  Neurol Clin Pract       Date:  2016-02

7.  Validation of a self-administered computerized system to detect cognitive impairment in older adults.

Authors:  Samuel D Brinkman; Robert J Reese; Larry A Norsworthy; Donna K Dellaria; Jacob W Kinkade; Jared Benge; Kimberly Brown; Anna Ratka; James W Simpkins
Journal:  J Appl Gerontol       Date:  2012-09-18

8.  Errors in self-reports of health services use: impact on alzheimer disease clinical trial designs.

Authors:  Christopher M Callahan; Wanzhu Tu; Timothy E Stump; Daniel O Clark; Kathleen T Unroe; Hugh C Hendrie
Journal:  Alzheimer Dis Assoc Disord       Date:  2015 Jan-Mar       Impact factor: 2.703

9.  Perception of Alzheimer's disease in the French population.

Authors:  A Breining; B Lavallart; S Pin; C Léon; S Moulias; P Arwidson; F Beck; C Berr; M Verny
Journal:  J Nutr Health Aging       Date:  2014-04       Impact factor: 4.075

10.  Structured approach to patients with memory difficulties in family practice.

Authors:  Linda Lee; W Wayne Weston; George Heckman; Micheline Gagnon; F Joseph Lee; Scott Sloka
Journal:  Can Fam Physician       Date:  2013-03       Impact factor: 3.275

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