Literature DB >> 19360168

Efficient kinetic resolution of racemic amines using a transaminase in combination with an amino acid oxidase.

Matthew D Truppo1, Nicholas J Turner, J David Rozzell.   

Abstract

A range of enantiomerically pure (R)- and (S)-configured chiral amines has been prepared in excellent e.e. (99%) by combining a transaminase enzyme with an amino acid oxidase and catalytic quantities of pyruvate.

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Year:  2009        PMID： 19360168     DOI： 10.1039/b902995h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  ω-Transaminase from Ochrobactrum anthropi is devoid of substrate and product inhibitions.

Authors:  Eul-Soo Park; Jong-Shik Shin
Journal:  Appl Environ Microbiol       Date:  2013-04-12       Impact factor: 4.792

2.  Asymmetric Preparation of prim-, sec-, and tert-Amines Employing Selected Biocatalysts.

Authors:  Wolfgang Kroutil; Eva-Maria Fischereder; Christine S Fuchs; Horst Lechner; Francesco G Mutti; Desiree Pressnitz; Aashrita Rajagopalan; Johann H Sattler; Robert C Simon; Elina Siirola
Journal:  Org Process Res Dev       Date:  2013-04-22       Impact factor: 3.317

3.  The Industrial Age of Biocatalytic Transamination.

Authors:  Michael Fuchs; Judith E Farnberger; Wolfgang Kroutil
Journal:  European J Org Chem       Date:  2015-09-23

4.  Stereo-Divergent Enzyme Cascades to Convert Racemic 4-Phenyl-2-Butanol into either (S)- or (R)-Corresponding Chiral Amine.

Authors:  Maria Romero-Fernandez; Francesca Paradisi
Journal:  Chembiochem       Date:  2022-03-03       Impact factor: 3.461

5.  Enzymatic and chemo-enzymatic strategies to produce highly valuable chiral amines from biomass with ω-transaminases on 2D zeolites.

Authors:  J Miguel Carceller; Karen S Arias; Maria J Climent; Sara Iborra; Avelino Corma
Journal:  Natl Sci Rev       Date:  2022-07-29       Impact factor: 23.178

6.  Recombinant l-Amino Acid Oxidase with Broad Substrate Spectrum for Co-substrate Recycling in (S)-Selective Transaminase-Catalyzed Kinetic Resolutions.

Authors:  Tobias Heinks; Jannik Paulus; Simon Koopmeiners; Tobias Beuel; Norbert Sewald; Matthias Höhne; Uwe T Bornscheuer; Gabriele Fischer von Mollard
Journal:  Chembiochem       Date:  2022-07-05       Impact factor: 3.461

7.  Exploiting cell metabolism for biocatalytic whole-cell transamination by recombinant Saccharomyces cerevisiae.

Authors:  Nora Weber; Marie Gorwa-Grauslund; Magnus Carlquist
Journal:  Appl Microbiol Biotechnol       Date:  2014-02-21       Impact factor: 4.813

8.  Concise Chemoenzymatic Three Step Total Synthesis of Isosolenopsin Through Medium Engineering.

Authors:  Robert C Simon; Christine S Fuchs; Horst Lechner; Ferdinand Zepeck; Wolfgang Kroutil
Journal:  European J Org Chem       Date:  2013-06-01
  8 in total

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