Literature DB >> 19350308

[Therapy of locally recurrent rectal carcinoma].

H G Hempen1, H R Raab.   

Abstract

During the last decade no gastrointestinal tumor underwent such profound modifications in diagnostics and therapy as rectal cancer (total mesorectal excision, multimodal therapy). Despite all efforts and continuous improvements in the results of oncological treatment, local recurrence of rectal carcinoma is still a considerable problem. Optimized surgery methods and multimodal therapies allow a local recurrence rate lowered to about 6%. Without surgical intervention the 5-year survival rate after local recurrence is approximately 4%, and the median survival time in a palliative situation is about 13 months and often associated with considerable restriction of quality of life. Morbidity after complex pelvic surgery is still high, but its mortality rate in highly professional surgical centers has reached an acceptable level of about 6%. Surgical oncology today has the ability for remarkable improvement in the prognosis of locally recurrent rectal cancer. After R0 resection the 5-year survival rate is nearly 30%.

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Mesh:

Year:  2009        PMID: 19350308     DOI: 10.1007/s00104-008-1622-7

Source DB:  PubMed          Journal:  Chirurg        ISSN: 0009-4722            Impact factor:   0.955


  29 in total

1.  Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer.

Authors:  E Kapiteijn; C A Marijnen; I D Nagtegaal; H Putter; W H Steup; T Wiggers; H J Rutten; L Pahlman; B Glimelius; J H van Krieken; J W Leer; C J van de Velde
Journal:  N Engl J Med       Date:  2001-08-30       Impact factor: 91.245

2.  Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Norwegian Adjuvant Rectal Cancer Project Group.

Authors:  K M Tveit; I Guldvog; S Hagen; E Trondsen; T Harbitz; K Nygaard; J B Nilsen; E Wist; E Hannisdal
Journal:  Br J Surg       Date:  1997-08       Impact factor: 6.939

Review 3.  Prognostic factors after surgery for locally recurrent rectal cancer: an overview.

Authors:  M Caricato; D Borzomati; F Ausania; S Valeri; A Rosignoli; R Coppola
Journal:  Eur J Surg Oncol       Date:  2005-12-27       Impact factor: 4.424

4.  Reirradiation, surgery and IORT for recurrent rectal cancer in previously irradiated patients.

Authors:  Maarten Vermaas; Joost J M E Nuyttens; Floris T J Ferenschild; Cornelis Verhoef; Alexander M M Eggermont; Johannes H W de Wilt
Journal:  Radiother Oncol       Date:  2008-03-18       Impact factor: 6.280

5.  Resection of isolated pelvic recurrences after colorectal surgery: long-term results and predictors of improved clinical outcome.

Authors:  Leonard R Henry; Elin Sigurdson; Eric A Ross; John S Lee; James C Watson; Jonathan D Cheng; Gary M Freedman; Andre Konski; John P Hoffman
Journal:  Ann Surg Oncol       Date:  2006-12-20       Impact factor: 5.344

6.  Improved survival with preoperative radiotherapy in resectable rectal cancer.

Authors:  B Cedermark; M Dahlberg; B Glimelius; L Påhlman; L E Rutqvist; N Wilking
Journal:  N Engl J Med       Date:  1997-04-03       Impact factor: 91.245

7.  Pre-operative MR assessment of recurrent rectal cancer.

Authors:  C Messiou; A G Chalmers; K Boyle; D Wilson; P Sagar
Journal:  Br J Radiol       Date:  2008-03-17       Impact factor: 3.039

8.  Radiochemotherapy in combination with regional hyperthermia in preirradiated patients with recurrent rectal cancer.

Authors:  Valeria Milani; Montserrat Pazos; Rolf Dieter Issels; Veit Buecklein; Sultan Rahman; Katharina Tschoep; Pamela Schaffer; Ralf Wilkowski; Eckhart Duehmke; Moshe Schaffer
Journal:  Strahlenther Onkol       Date:  2008-03       Impact factor: 3.621

9.  Presentation and prognosis of local recurrence after total mesorectal excision.

Authors:  C de Chaisemartin; C Penna; D Goere; S Benoist; A Beauchet; C Julie; B Nordlinger
Journal:  Colorectal Dis       Date:  2008-04-28       Impact factor: 3.788

10.  Reirradiation and hyperthermia in rectal carcinoma: a retrospective study on palliative effect.

Authors:  Jorine H M Juffermans; Patrick E J Hanssens; Wim L J van Putten; Gerard C van Rhoon; Jacoba van Der Zee
Journal:  Cancer       Date:  2003-10-15       Impact factor: 6.860

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  2 in total

1.  Locally recurrent colorectal cancer: results of surgical therapy.

Authors:  M Kruschewski; M Ciurea; S Lipka; S Daum; L Moser; B Meyer; J Gröne; J Budczies; H J Buhr
Journal:  Langenbecks Arch Surg       Date:  2012-06-28       Impact factor: 3.445

Review 2.  [Imaging: The oncologist's perspective].

Authors:  S Fuxius
Journal:  Radiologe       Date:  2020-12-18       Impact factor: 0.635

  2 in total

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