Literature DB >> 19347026

Delirium in elderly adults: diagnosis, prevention and treatment.

Tamara G Fong1, Samir R Tulebaev, Sharon K Inouye.   

Abstract

Delirium is a common and serious acute neuropsychiatric syndrome with core features of inattention and global cognitive dysfunction. The etiologies of delirium are diverse and multifactorial and often reflect the pathophysiological consequences of an acute medical illness, medical complication or drug intoxication. Delirium can have a widely variable presentation, and is often missed and underdiagnosed as a result. At present, the diagnosis of delirium is clinically based and depends on the presence or absence of certain features. Management strategies for delirium are focused on prevention and symptom management. This article reviews current clinical practice in delirium in elderly individuals, including the diagnosis, treatment, outcomes and economic impact of this syndrome. Areas of future research are also discussed.

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Year:  2009        PMID: 19347026      PMCID: PMC3065676          DOI: 10.1038/nrneurol.2009.24

Source DB:  PubMed          Journal:  Nat Rev Neurol        ISSN: 1759-4758            Impact factor:   42.937


  111 in total

Review 1.  The role of neuroimaging in elucidating delirium pathophysiology.

Authors:  David C Alsop; Michael A Fearing; Keith Johnson; Reisa Sperling; Tamara G Fong; Sharon K Inouye
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2006-12       Impact factor: 6.053

2.  Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients.

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Journal:  Arch Intern Med       Date:  2001-04-23

3.  Validating the diagnosis of delirium and evaluating its association with deterioration over a one-year period.

Authors:  I R Katz; K J Curyto; T TenHave; J Mossey; L Sands; M J Kallan
Journal:  Am J Geriatr Psychiatry       Date:  2001       Impact factor: 4.105

4.  Reducing acute confusional states in elderly patients with hip fractures.

Authors:  M A Williams; E B Campbell; W J Raynor; S M Mlynarczyk; S E Ward
Journal:  Res Nurs Health       Date:  1985-12       Impact factor: 2.228

5.  Prevention of psychosis following open-heart surgery.

Authors:  H R Lazarus; J H Hagens
Journal:  Am J Psychiatry       Date:  1968-03       Impact factor: 18.112

6.  A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement.

Authors:  Elizabeth L Sampson; Peter R Raven; Patricia N Ndhlovu; Aaron Vallance; Nicholas Garlick; Julie Watts; Martin R Blanchard; Angela Bruce; Robert Blizard; Craig W Ritchie
Journal:  Int J Geriatr Psychiatry       Date:  2007-04       Impact factor: 3.485

7.  The role of adherence on the effectiveness of nonpharmacologic interventions: evidence from the delirium prevention trial.

Authors:  Sharon K Inouye; Sidney T Bogardus; Christianna S Williams; Linda Leo-Summers; Joseph V Agostini
Journal:  Arch Intern Med       Date:  2003-04-28

8.  Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease.

Authors:  Colm Cunningham; Suzanne Campion; Katie Lunnon; Carol L Murray; Jack F C Woods; Robert M J Deacon; J Nicholas P Rawlins; V Hugh Perry
Journal:  Biol Psychiatry       Date:  2008-09-18       Impact factor: 13.382

9.  Time-course of cytokines during delirium in elderly patients with hip fractures.

Authors:  Barbara C van Munster; Johanna C Korevaar; Aeilko H Zwinderman; Marcel Levi; W Joost Wiersinga; Sophia E De Rooij
Journal:  J Am Geriatr Soc       Date:  2008-08-04       Impact factor: 5.562

10.  Delirium in critical care unit patients admitted through an emergency room.

Authors:  Y Kishi; Y Iwasaki; K Takezawa; H Kurosawa; S Endo
Journal:  Gen Hosp Psychiatry       Date:  1995-09       Impact factor: 3.238

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  196 in total

Review 1.  Agitation and Irritability in Alzheimer's Disease: Evidenced-Based Treatments and the Black-Box Warning.

Authors:  Aaron M Koenig; Steven E Arnold; Joel E Streim
Journal:  Curr Psychiatry Rep       Date:  2016-01       Impact factor: 5.285

Review 2.  [Management of delirium in the intensive care unit : Non-pharmacological therapy options].

Authors:  N Zoremba
Journal:  Med Klin Intensivmed Notfmed       Date:  2015-12-14       Impact factor: 0.840

3.  New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study.

Authors:  Sarinnapha M Vasunilashorn; Dena Schulman-Green; Douglas Tommet; Tamara G Fong; Tammy T Hshieh; Edward R Marcantonio; Eran D Metzger; Eva M Schmitt; Patricia A Tabloski; Thomas G Travison; Yun Gou; Benjamin Helfand; Sharon K Inouye; Richard N Jones
Journal:  Dement Geriatr Cogn Disord       Date:  2020-06-17       Impact factor: 2.959

4.  Delirium Prediction using Machine Learning Models on Preoperative Electronic Health Records Data.

Authors:  Anis Davoudi; Ashkan Ebadi; Parisa Rashidi; Tazcan Ozrazgat-Baslanti; Azra Bihorac; Alberto C Bursian
Journal:  Proc IEEE Int Symp Bioinformatics Bioeng       Date:  2018-01-11

5.  Association between Inpatient Delirium and Hospital Readmission in Patients ≥ 65 Years of Age: A Retrospective Cohort Study.

Authors:  Sara C LaHue; Vanja C Douglas; Teresa Kuo; Carol A Conell; Vincent X Liu; S Andrew Josephson; Clay Angel; Kristen B Brooks
Journal:  J Hosp Med       Date:  2019-04       Impact factor: 2.960

Review 6.  Cigarette smoking as a risk factor for delirium in hospitalized and intensive care unit patients. A systematic review.

Authors:  S Jean Hsieh; Mili Shum; Andrew N Lee; Fairouz Hasselmark; Michelle N Gong
Journal:  Ann Am Thorac Soc       Date:  2013-10

7.  Physician Information Needs in Managing Delirium.

Authors:  Teresa Taft; Scott D Nelsen; Stacey Slager; Charlene Weir
Journal:  AMIA Annu Symp Proc       Date:  2018-04-16

8.  Preoperative Risk Factors for Subsyndromal Delirium in Older Adults Who Undergo Joint Replacement Surgery.

Authors:  Dawn L Denny; Glenda Lindseth
Journal:  Orthop Nurs       Date:  2017 Nov/Dec       Impact factor: 0.913

9.  POETenceph - Automatic identification of clinical notes indicating encephalopathy using a realist ontology.

Authors:  Kristina M Doing-Harris; Charlene R Weir; Sean Igo; Jianlin Shi; Yijun Shao; John F Hurdle
Journal:  AMIA Annu Symp Proc       Date:  2015-11-05

10.  Identifying risk of readmission in hospitalized elderly adults through inpatient medication exposure.

Authors:  Juliessa M Pavon; Yanfang Zhao; Eleanor McConnell; S Nicole Hastings
Journal:  J Am Geriatr Soc       Date:  2014-05-06       Impact factor: 5.562

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