Literature DB >> 19346850

A comprehensive electrocardiogram-gated 64-slice multidetector computed tomography imaging protocol to visualize the coronary arteries, thoracic aorta, and pulmonary vasculature in a single breath hold.

Michael D Shapiro1, Jonathan D Dodd, Sanjeeva Kalva, Conrad Wittram, Joe Hsu, Khurram Nasir, Bob Liu, John T Nagurney, Mannudeep K Kalra, John H Nichols, Ricardo C Cury, Suhny Abbara, Ahmed Tawakol, Thomas J Brady, Udo Hoffmann.   

Abstract

OBJECTIVES: Advances in computed tomography technology may permit the evaluation of coronary disease, aortic dissection, and pulmonary embolism with a single contrast bolus and breath hold. We sought to determine whether 64-slice computed tomography angiography (CTA) allows for simultaneous visualization of the coronary arteries, thoracic aorta, and pulmonary arteries (coronary, aorta, pulmonary [CAP]) with image quality comparable to routine CTA protocols.
MATERIALS AND METHODS: We prospectively enrolled 20 patients who underwent CAP CTA. Image quality of CAP CTA was assessed qualitatively and quantitatively and compared with dedicated coronary (n = 20) and pulmonary (n = 10) CTA data sets using matched controls.
RESULTS: The mean amount of contrast and radiation dose was 132 +/- 10 mL and 17.8 +/- 1.8 mSv, 78 +/- 9 mL and 13.7 +/- 3.4 mSv, and 135 mL and 11.9 +/- 1.5 mSv for CAP CTA, coronary CTA, and pulmonary CTA, respectively (P = 0.001). There was no difference in overall image quality (P = 0.88), presence of motion artifacts (P = 0.40), or enhancement of the proximal coronary arteries (median [interquartile range for contrast-noise ratio was 12.5 9.9-15.2 vs 13.1 10.3-16.9; P = 0.17]) or thoracic aorta (264 [113-326] vs 245 [107-295]; P = 0.34) between CAP CTA and the dedicated coronary CTA, respectively. However, contrast attenuation was higher in the pulmonary arteries with CAP CTA (363 [253-424]) versus the standard pulmonary CTA protocol (235 [182-269]; P = 0.0001).
CONCLUSIONS: : Using an individually tailored single contrast injection, CAP CTA permits simultaneous visualization of the coronary arteries, thoracic aorta, and pulmonary arteries with excellent image quality. Further research is necessary to determine whether this protocol may enhance triage of patients with undifferentiated acute chest pain.

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Year:  2009        PMID: 19346850     DOI: 10.1097/RCT.0b013e31817c12b1

Source DB:  PubMed          Journal:  J Comput Assist Tomogr        ISSN: 0363-8715            Impact factor:   1.826


  7 in total

1.  High-pitch dual-source CT angiography of the aortic valve-aortic root complex without ECG-synchronization.

Authors:  Christoph Karlo; Sebastian Leschka; Robert Paul Goetti; Gudrun Feuchtner; Lotus Desbiolles; Paul Stolzmann; Andre Plass; Volkmar Falk; Borut Marincek; Hatem Alkadhi; Stephan Baumüller
Journal:  Eur Radiol       Date:  2010-07-31       Impact factor: 5.315

2.  Diagnostic performance of state-of-the-art imaging techniques for morphological assessment of vascular abnormalities in patients with chronic thromboembolic pulmonary hypertension (CTEPH).

Authors:  Sebastian Ley; Julia Ley-Zaporozhan; Michael B Pitton; Jens Schneider; Gesine M Wirth; Eckhard Mayer; Christoph Düber; Karl-Friedrich Kreitner
Journal:  Eur Radiol       Date:  2011-09-27       Impact factor: 5.315

3.  High-pitch dual-source CT coronary angiography: systolic data acquisition at high heart rates.

Authors:  Robert Goetti; Gudrun Feuchtner; Paul Stolzmann; Lotus Desbiolles; Michael Alexander Fischer; Christoph Karlo; Stephan Baumueller; Hans Scheffel; Hatem Alkadhi; Sebastian Leschka
Journal:  Eur Radiol       Date:  2010-06-29       Impact factor: 5.315

Review 4.  Testing of low-risk patients presenting to the emergency department with chest pain: a scientific statement from the American Heart Association.

Authors:  Ezra A Amsterdam; J Douglas Kirk; David A Bluemke; Deborah Diercks; Michael E Farkouh; J Lee Garvey; Michael C Kontos; James McCord; Todd D Miller; Anthony Morise; L Kristin Newby; Frederick L Ruberg; Kristine Anne Scordo; Paul D Thompson
Journal:  Circulation       Date:  2010-07-26       Impact factor: 29.690

5.  Diagnostic Value of Transthoracic Echocardiography in Patients With Anomalous Origin of the Left Coronary Artery From the Pulmonary Artery.

Authors:  Rong-Juan Li; Zhonghua Sun; Jiao Yang; Ya Yang; Yi-Jia Li; Zhao-Ting Leng; Guo-Wen Liu; Li-Hong Pu
Journal:  Medicine (Baltimore)       Date:  2016-04       Impact factor: 1.889

6.  Diagnostic Accuracy of Electrocardiogram-Gated Thoracic Computed Tomography Angiography without Heart Rate Control for Detection of Significant Coronary Artery Stenosis in Patients with Acute Ischemic Stroke: A Comparative Study.

Authors:  Inyoung Song; Ji Hun Kang; Mi Young Kim; Hweung Kon Hwang; Han Young Kim; Sung Min Ko
Journal:  Korean J Radiol       Date:  2018-08-06       Impact factor: 3.500

7.  Echocardiographic diagnosis of anomalous origin of the left coronary artery from the pulmonary artery.

Authors:  Xin-Chun Yuan; Jia Hu; Xi Zeng; Ai-Yun Zhou; Li Chen
Journal:  Medicine (Baltimore)       Date:  2019-11       Impact factor: 1.817

  7 in total

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