Literature DB >> 19345321

Unraveling the complexities of androgen receptor signaling in prostate cancer cells.

Hannelore V Heemers1, Donald J Tindall.   

Abstract

Androgen signaling is critical for proliferation of prostate cancer cells but cannot be fully inhibited by current androgen deprivation therapies. A study by Xu et al. in this issue of Cancer Cell provides insights into the complexities of androgen signaling in prostate cancer and suggests avenues to target a subset of androgen-sensitive genes.

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Year:  2009        PMID： 19345321      PMCID： PMC2718563          DOI： 10.1016/j.ccr.2009.03.009

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

1.  Mechanisms of androgen-refractory prostate cancer.

Authors:  Jose D Debes; Donald J Tindall
Journal:  N Engl J Med       Date:  2004-10-07       Impact factor: 91.245

2.  Androgen modulation of coregulator expression in prostate cancer cells.

Authors:  Hannelore V Heemers; Kevin M Regan; Lucy J Schmidt; S Keith Anderson; Karla V Ballman; Donald J Tindall
Journal:  Mol Endocrinol       Date:  2009-01-22

3.  Words of wisdom. Re: Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. Attard G, Reide AHM, Yap TA, Raynaud F, Dowsett M, Settatree S, Barrett M, Parker C, Martins V, Folkerd E, Clark J, Cooper C, Kaye S, Dearnaley D, Lee G, de Bono JS. J Clin Oncol 2008;26:4563-71.

Authors:  Mario A Eisenberger
Journal:  Eur Urol       Date:  2009-01       Impact factor: 20.096

4.  Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways.

Authors:  Ray-Chang Wu; Jun Qin; Ping Yi; Jiemin Wong; Sophia Y Tsai; Ming-Jer Tsai; Bert W O'Malley
Journal:  Mol Cell       Date:  2004-09-24       Impact factor: 17.970

Review 5.  Targeting the androgen receptor pathway in prostate cancer.

Authors:  Yu Chen; Charles L Sawyers; Howard I Scher
Journal:  Curr Opin Pharmacol       Date:  2008-08-12       Impact factor: 5.547

Review 6.  Castration-recurrent prostate cancer is not androgen-independent.

Authors:  James L Mohler
Journal:  Adv Exp Med Biol       Date:  2008       Impact factor: 2.622

Review 7.  Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex.

Authors:  Hannelore V Heemers; Donald J Tindall
Journal:  Endocr Rev       Date:  2007-10-16       Impact factor: 19.871

8.  Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination.

Authors:  Kexin Xu; Hermela Shimelis; Douglas E Linn; Richeng Jiang; Xi Yang; Feng Sun; Zhiyong Guo; Hege Chen; Wei Li; Hegang Chen; Xiangtian Kong; Jonathan Melamed; Shengyun Fang; Zhen Xiao; Timothy D Veenstra; Yun Qiu
Journal:  Cancer Cell       Date:  2009-04-07       Impact factor: 31.743

9.  Genomic androgen receptor-occupied regions with different functions, defined by histone acetylation, coregulators and transcriptional capacity.

Authors:  Li Jia; Benjamin P Berman; Unnati Jariwala; Xiting Yan; Jon P Cogan; Allison Walters; Ting Chen; Grant Buchanan; Baruch Frenkel; Gerhard A Coetzee
Journal:  PLoS One       Date:  2008-11-10       Impact factor: 3.240
  9 in total
  13 in total

Review 1.  Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development.

Authors:  W-L Yang; X Zhang; H-K Lin
Journal:  Oncogene       Date:  2010-06-07       Impact factor: 9.867

2.  The Deubiquitinating Enzyme USP7 Regulates Androgen Receptor Activity by Modulating Its Binding to Chromatin.

Authors:  Shu-Ting Chen; Maiko Okada; Ryuichiro Nakato; Kosuke Izumi; Masashige Bando; Katsuhiko Shirahige
Journal:  J Biol Chem       Date:  2015-07-14       Impact factor: 5.157

Review 3.  Targeting 5α-reductase for prostate cancer prevention and treatment.

Authors:  Lucas P Nacusi; Donald J Tindall
Journal:  Nat Rev Urol       Date:  2011-05-31       Impact factor: 14.432

4.  ChIP-seq analysis of androgen receptor in LNCaP cell line.

Authors:  Sifeng Tao; Haifei He; Qiang Chen
Journal:  Mol Biol Rep       Date:  2014-07-02       Impact factor: 2.316

Review 5.  Back to your heart: ubiquitin proteasome system-regulated signal transduction.

Authors:  Andrea L Portbury; Sarah M Ronnebaum; Makhosazane Zungu; Cam Patterson; Monte S Willis
Journal:  J Mol Cell Cardiol       Date:  2011-11-06       Impact factor: 5.000

6.  Androgen receptor abnormalities in castration-recurrent prostate cancer.

Authors:  Lucas P Nacusi; Donald J Tindall
Journal:  Expert Rev Endocrinol Metab       Date:  2009-09-01

7.  Characterization of androgen receptor structure and nucleocytoplasmic shuttling of the rice field eel.

Authors:  Fang Zhou; Wei Zhao; Zhixiang Zuo; Yue Sheng; Xiang Zhou; Yu Hou; Hanhua Cheng; Rongjia Zhou
Journal:  J Biol Chem       Date:  2010-09-14       Impact factor: 5.157

Review 8.  Androgen Signaling in Prostate Cancer.

Authors:  Charles Dai; Hannelore Heemers; Nima Sharifi
Journal:  Cold Spring Harb Perspect Med       Date:  2017-09-01       Impact factor: 6.915

9.  Peptidomimetic targeting of critical androgen receptor-coregulator interactions in prostate cancer.

Authors:  Preethi Ravindranathan; Tae-Kyung Lee; Lin Yang; Margaret M Centenera; Lisa Butler; Wayne D Tilley; Jer-Tsong Hsieh; Jung-Mo Ahn; Ganesh V Raj
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

10.  RING-finger protein 6 enhances c-Myc-mediated Warburg effect by promoting MAD1 degradation to facilitate pancreatic cancer metastasis.

Authors:  Yumin Qiu; Hengqing Zhu; Debin Xu; Qian Feng; Chongyu Wen; Yunyan Du; Mingfeng Xiang; Leifeng Chen; Xiaogang Peng
Journal:  Am J Cancer Res       Date:  2021-05-15       Impact factor: 6.166
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