Literature DB >> 19343034

Tumour necrosis factor and cancer.

Frances Balkwill1.   

Abstract

Tumour necrosis factor (TNF) is a major inflammatory cytokine that was first identified for its ability to induce rapid haemorrhagic necrosis of experimental cancers. When efforts to harness this anti-tumour activity in cancer treatments were underway, a paradoxical tumour-promoting role of TNF became apparent. Now that links between inflammation and cancer are appreciated, is TNF a target or a therapeutic in malignant disease -- or both?

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19343034     DOI： 10.1038/nrc2628

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  165 in total

1.  Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

Authors:  M Fràter-Schröder; W Risau; R Hallmann; P Gautschi; P Böhlen
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

2.  Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial.

Authors:  U Chaudhari; P Romano; L D Mulcahy; L T Dooley; D G Baker; A B Gottlieb
Journal:  Lancet       Date:  2001-06-09       Impact factor: 79.321

3.  Recombinant tumor necrosis factor: its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines.

Authors:  L Fransen; J Van der Heyden; R Ruysschaert; W Fiers
Journal:  Eur J Cancer Clin Oncol       Date:  1986-04

4.  Constitutive expression and role of the TNF family ligands in apoptotic killing of tumor cells by human NK cells.

Authors:  Y Kashii; R Giorda; R B Herberman; T L Whiteside; N L Vujanovic
Journal:  J Immunol       Date:  1999-11-15       Impact factor: 5.422

Review 5.  Development of anti-TNF therapy for rheumatoid arthritis.

Authors:  Marc Feldmann
Journal:  Nat Rev Immunol       Date:  2002-05       Impact factor: 53.106

6.  Inhibitory effect of TNF alpha antibodies on synovial cell interleukin-1 production in rheumatoid arthritis.

Authors:  F M Brennan; D Chantry; A Jackson; R Maini; M Feldmann
Journal:  Lancet       Date:  1989-07-29       Impact factor: 79.321

7.  Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis.

Authors:  Sean L Petersen; Lai Wang; Asligul Yalcin-Chin; Lin Li; Michael Peyton; John Minna; Patrick Harran; Xiaodong Wang
Journal:  Cancer Cell       Date:  2007-11       Impact factor: 31.743

8.  A phase II study of etanercept (Enbrel), a tumor necrosis factor alpha inhibitor in patients with metastatic breast cancer.

Authors:  Srinivasan Madhusudan; Martin Foster; Sethupathi R Muthuramalingam; Jeremy P Braybrooke; Susan Wilner; Kulwinder Kaur; Cheng Han; Susan Hoare; Frances Balkwill; Denis C Talbot; Trivadi S Ganesan; Adrian L Harris
Journal:  Clin Cancer Res       Date:  2004-10-01       Impact factor: 12.531

9.  Adaptive immunity maintains occult cancer in an equilibrium state.

Authors:  Catherine M Koebel; William Vermi; Jeremy B Swann; Nadeen Zerafa; Scott J Rodig; Lloyd J Old; Mark J Smyth; Robert D Schreiber
Journal:  Nature       Date:  2007-11-18       Impact factor: 49.962

10.  Translational strategies exploiting TNF-alpha that sensitize tumors to radiation therapy.

Authors:  H J Mauceri; M A Beckett; H Liang; H G Sutton; S Pitroda; E Galka; E Efimova; T Darga; N N Khodarev; C R King; M C Posner; S Hellman; D W Kufe; R R Weichselbaum
Journal:  Cancer Gene Ther       Date:  2008-10-31       Impact factor: 5.987
View more
  628 in total

1.  Role of STK in mouse liver macrophage and endothelial cell responsiveness during acute endotoxemia.

Authors:  Debra L Laskin; Li Chen; Pamela A Hankey; Jeffrey D Laskin
Journal:  J Leukoc Biol       Date:  2010-05-07       Impact factor: 4.962

2.  Oncogene-driven intrinsic inflammation induces leukocyte production of tumor necrosis factor that critically contributes to mammary carcinogenesis.

Authors:  Sabina Sangaletti; Claudio Tripodo; Chiara Ratti; Silvia Piconese; Rossana Porcasi; Rosalba Salcedo; Giorgio Trinchieri; Mario P Colombo; Claudia Chiodoni
Journal:  Cancer Res       Date:  2010-10-05       Impact factor: 12.701

3.  TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer.

Authors:  Hai Lu; Xinping Yang; Praveen Duggal; Clint T Allen; Bin Yan; Jonah Cohen; Liesl Nottingham; Rose-Anne Romano; Satrajit Sinha; Kathryn E King; Wendy C Weinberg; Zhong Chen; Carter Van Waes
Journal:  Cancer Res       Date:  2011-09-20       Impact factor: 12.701

Review 4.  Macrophage-tumor crosstalk: role of TAMR tyrosine kinase receptors and of their ligands.

Authors:  Thomas Schmidt; Isabel Ben-Batalla; Alexander Schultze; Sonja Loges
Journal:  Cell Mol Life Sci       Date:  2011-11-11       Impact factor: 9.261

5.  Natural killer cell-produced IFN-γ and TNF-α induce target cell cytolysis through up-regulation of ICAM-1.

Authors:  Ruipeng Wang; Jessica J Jaw; Nicole C Stutzman; Zhongcheng Zou; Peter D Sun
Journal:  J Leukoc Biol       Date:  2011-11-01       Impact factor: 4.962

Review 6.  Concordance of preclinical and clinical pharmacology and toxicology of monoclonal antibodies and fusion proteins: soluble targets.

Authors:  Pauline L Martin; Peter J Bugelski
Journal:  Br J Pharmacol       Date:  2012-06       Impact factor: 8.739

Review 7.  Inhibiting the inhibitors: evaluating agents targeting cancer immunosuppression.

Authors:  Theresa L Whiteside
Journal:  Expert Opin Biol Ther       Date:  2010-07       Impact factor: 4.388

Review 8.  Immunity, inflammation, and cancer.

Authors:  Sergei I Grivennikov; Florian R Greten; Michael Karin
Journal:  Cell       Date:  2010-03-19       Impact factor: 41.582

9.  ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression.

Authors:  Wei Wang; Ka Bian; Sreeram Vallabhaneni; Bin Zhang; Ray-Chang Wu; Bert W O'Malley; Weiwen Long
Journal:  J Cell Physiol       Date:  2014-10       Impact factor: 6.384

Review 10.  The association between metabolic syndrome and colorectal neoplasm: systemic review and meta-analysis.

Authors:  Raxitkumar Jinjuvadia; Prateek Lohia; Chetna Jinjuvadia; Sergio Montoya; Suthat Liangpunsakul
Journal:  J Clin Gastroenterol       Date:  2013-01       Impact factor: 3.062
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.