Literature DB >> 19342780

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the SH3 domain of human AHI1.

Zhuliang Shi1, Ning Liang, Wei Xu, Kuai Li, Guoqing Sheng, Jinsong Liu, Aimin Xu, Xiao Jiang Li, Donghai Wu.   

Abstract

The SH3 domain of human AHI1 was cloned and expressed in Escherichia coli. The protein was purified by affinity and size-exclusion chromatography and was crystallized using the sitting-drop vapour-diffusion method at 293 K. A complete data set was collected to 2.5 A resolution at 110 K. The crystal belonged to space group P4(1)2(1)2, with unit-cell parameters a = 67.377, b = 67.377, c = 98.549 A.

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Year:  2009        PMID: 19342780      PMCID: PMC2664760          DOI: 10.1107/S174430910900774X

Source DB:  PubMed          Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun        ISSN: 1744-3091


  13 in total

1.  Solvent content of protein crystals.

Authors:  B W Matthews
Journal:  J Mol Biol       Date:  1968-04-28       Impact factor: 5.469

2.  Joubert syndrome (and related disorders) (OMIM 213300).

Authors:  Melissa A Parisi; Dan Doherty; Phillip F Chance; Ian A Glass
Journal:  Eur J Hum Genet       Date:  2007-03-21       Impact factor: 4.246

3.  High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides.

Authors:  A Musacchio; M Saraste; M Wilmanns
Journal:  Nat Struct Biol       Date:  1994-08

4.  Identification of the first AHI1 gene mutations in nephronophthisis-associated Joubert syndrome.

Authors:  Boris Utsch; John A Sayer; Massimo Attanasio; Rob Rodrigues Pereira; Michael Eccles; Hans-Christian Hennies; Edgar A Otto; Friedhelm Hildebrandt
Journal:  Pediatr Nephrol       Date:  2005-10-21       Impact factor: 3.714

5.  AHI1 gene mutations cause specific forms of Joubert syndrome-related disorders.

Authors:  Enza Maria Valente; Francesco Brancati; Jennifer L Silhavy; Marco Castori; Sarah E Marsh; Giuseppe Barrano; Enrico Bertini; Eugen Boltshauser; Maha S Zaki; Alice Abdel-Aleem; Ghada M H Abdel-Salam; Emanuele Bellacchio; Roberta Battini; Robert P Cruse; William B Dobyns; Kalpathy S Krishnamoorthy; Clotilde Lagier-Tourenne; Alex Magee; Ignacio Pascual-Castroviejo; Carmelo D Salpietro; Dean Sarco; Bruno Dallapiccola; Joseph G Gleeson
Journal:  Ann Neurol       Date:  2006-03       Impact factor: 10.422

6.  Abnormal cerebellar development and axonal decussation due to mutations in AHI1 in Joubert syndrome.

Authors:  Russell J Ferland; Wafaa Eyaid; Randall V Collura; Laura D Tully; R Sean Hill; Doha Al-Nouri; Ahmed Al-Rumayyan; Meral Topcu; Generoso Gascon; Adria Bodell; Yin Yao Shugart; Maryellen Ruvolo; Christopher A Walsh
Journal:  Nat Genet       Date:  2004-08-22       Impact factor: 38.330

7.  Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice.

Authors:  Guoqing Sheng; Xingshun Xu; Yung-Feng Lin; Chuan-En Wang; Juan Rong; Dongmei Cheng; Junmin Peng; Xiaoyan Jiang; Shi-Hua Li; Xiao-Jiang Li
Journal:  J Clin Invest       Date:  2008-08       Impact factor: 14.808

8.  Ahi-1, a novel gene encoding a modular protein with WD40-repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations.

Authors:  Xiaoyan Jiang; Zaher Hanna; Mohammadi Kaouass; Luc Girard; Paul Jolicoeur
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

9.  DNA analysis of AHI1, NPHP1 and CYCLIN D1 in Joubert syndrome patients from the Netherlands.

Authors:  Hester Y Kroes; Patrick H A van Zon; Dietje Fransen van de Putte; Marcel R Nelen; Rutger-Jan Nievelstein; Dienke Wittebol-Post; Onno van Nieuwenhuizen; Grazia M S Mancini; Marjo S van der Knaap; Mei Lan Kwee; Saskia M Maas; Jan Maarten Cobben; Jacques E E De Nef; Dick Lindhout; Richard J Sinke
Journal:  Eur J Med Genet       Date:  2007-10-06       Impact factor: 2.708

Review 10.  SH3 domains: complexity in moderation.

Authors:  B J Mayer
Journal:  J Cell Sci       Date:  2001-04       Impact factor: 5.285

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  1 in total

1.  Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development.

Authors:  Roslyn J Simms; Ann Marie Hynes; Lorraine Eley; David Inglis; Bill Chaudhry; Helen R Dawe; John A Sayer
Journal:  Cell Mol Life Sci       Date:  2011-09-29       Impact factor: 9.261

  1 in total

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