Literature DB >> 19341847

Side effects from the copper IUD: do they decrease over time?

David Hubacher1, Pai-Lien Chen, Sola Park.   

Abstract

BACKGROUND: The copper intrauterine device (IUD) can cause side effects in some women; increased uterine bleeding and pain may cause early removal. Because of simplified reporting from previous research, little is known about how side effects might change over time. STUDY
DESIGN: This is a secondary analysis of a prospective study of 1947 first-time copper IUD users. Over a 1-year period, we collected detailed information on side effects and looked for trends using generalized mixed-effects regression modeling.
RESULTS: During menses, most bleeding and pain side effects were found to decrease over time (p<.05). During intermenstrual intervals, overall spotting and pain complaints remained unchanged, but the number of days with these problems increased (p<.05). Serious side effects that prompted either a clinic visit or IUD removal had varied patterns over time, depending on the type of problem.
CONCLUSION: Side effects from the copper IUD can be troubling for both user and clinician. Some problems improve over time, while others do not. This information may be helpful in counseling women who are considering IUD use and current users who are contemplating IUD removal due to side effects.

Entities:  

Mesh:

Year:  2009        PMID: 19341847      PMCID: PMC2702765          DOI: 10.1016/j.contraception.2008.11.012

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  16 in total

1.  Assessing response profiles from incomplete longitudinal clinical trial data under regulatory considerations.

Authors:  Craig H Mallinckrodt; S W Scott Clark; Raymond J Carroll; Geert Molenbergh
Journal:  J Biopharm Stat       Date:  2003-05       Impact factor: 1.051

2.  Longitudinal data analysis for discrete and continuous outcomes.

Authors:  S L Zeger; K Y Liang
Journal:  Biometrics       Date:  1986-03       Impact factor: 2.571

3.  Contraceptive efficacy of the Copper T380A and the Multiload Cu250 IUD in three developing countries.

Authors:  G Farr; R Amatya
Journal:  Adv Contracept       Date:  1994-06

Review 4.  Quantitative studies on menstrual blood loss in IUD users.

Authors:  A T Andrade; E Pizarro Orchard
Journal:  Contraception       Date:  1987-07       Impact factor: 3.375

5.  Health during prolonged use of levonorgestrel 20 micrograms/d and the copper TCu 380Ag intrauterine contraceptive devices: a multicenter study. International Committee for Contraception Research (ICCR).

Authors:  I Sivin; J Stern
Journal:  Fertil Steril       Date:  1994-01       Impact factor: 7.329

6.  The analysis of vaginal bleeding patterns induced by fertility regulating methods. World Health Organization Special Programme of Research, Development and Research Training in Human Reproduction.

Authors:  E M Belsey; D Machin; C d'Arcangues
Journal:  Contraception       Date:  1986-09       Impact factor: 3.375

7.  The long-term effects of copper surface area on menstrual blood loss and iron status in women fitted with an IUD.

Authors:  G Larsson; I Milsom; K Jonasson; G Lindstedt; G Rybo
Journal:  Contraception       Date:  1993-11       Impact factor: 3.375

Review 8.  Copper-containing, framed intrauterine devices for contraception: a systematic review of randomized controlled trials.

Authors:  Paul A O'Brien; Regina Kulier; Frans M Helmerhorst; Margaret Usher-Patel; Catherine d'Arcangues
Journal:  Contraception       Date:  2008-03-18       Impact factor: 3.375

9.  Intrauterine contraception with copper and with levonorgestrel: a randomized study of the TCu 380Ag and levonorgestrel 20 mcg/day devices.

Authors:  I Sivin; F Alvarez; J Diaz; S Diaz; S el Mahgoub; E Coutinho; V Brache; M M Diaz; A Faundes; M Pavez
Journal:  Contraception       Date:  1984-11       Impact factor: 3.375

10.  Assessing changes in vaginal bleeding patterns in contracepting women.

Authors:  D Machin; T M Farley; B Busca; M J Campbell; C d'Arcangues
Journal:  Contraception       Date:  1988-08       Impact factor: 3.375

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  23 in total

1.  Copper intrauterine device for emergency contraception: clinical practice among contraceptive providers.

Authors:  Cynthia C Harper; J Joseph Speidel; Eleanor A Drey; James Trussell; Maya Blum; Philip D Darney
Journal:  Obstet Gynecol       Date:  2012-02       Impact factor: 7.661

Review 2.  Biomaterials and Contraception: Promises and Pitfalls.

Authors:  Isabella Claure; Deborah Anderson; Catherine M Klapperich; Wendy Kuohung; Joyce Y Wong
Journal:  Ann Biomed Eng       Date:  2019-11-07       Impact factor: 3.934

Review 3.  Emergency contraception review: evidence-based recommendations for clinicians.

Authors:  Kelly Cleland; Elizabeth G Raymond; Elizabeth Westley; James Trussell
Journal:  Clin Obstet Gynecol       Date:  2014-12       Impact factor: 2.190

4.  Elevated Risk of Bacterial Vaginosis Among Users of the Copper Intrauterine Device: A Prospective Longitudinal Cohort Study.

Authors:  Kathryn Peebles; Flavia M Kiweewa; Thesla Palanee-Phillips; Catherine Chappell; Devika Singh; Katherine E Bunge; Logashvari Naidoo; Bonus Makanani; Nitesha Jeenarain; Doerieyah Reynolds; Sharon L Hillier; Elizabeth R Brown; Jared M Baeten; Jennifer E Balkus
Journal:  Clin Infect Dis       Date:  2021-08-02       Impact factor: 9.079

Review 5.  Efficacy and safety of long-acting reversible contraception.

Authors:  Amy Stoddard; Colleen McNicholas; Jeffrey F Peipert
Journal:  Drugs       Date:  2011-05-28       Impact factor: 9.546

6.  A study of physician recommendations for reversible contraceptive methods using standardized patients.

Authors:  Christine Dehlendorf; Kevin Grumbach; Eric Vittinghoff; Rachel Ruskin; Jody Steinauer
Journal:  Perspect Sex Reprod Health       Date:  2011-11-04

Review 7.  New developments in long-acting reversible contraception: the promise of intrauterine devices and implants to improve family planning services.

Authors:  David K Turok; Lori M Gawron; Samantha Lawson
Journal:  Fertil Steril       Date:  2016-10-04       Impact factor: 7.329

8.  A randomized controlled trial of daily text messages versus monthly paper diaries to collect bleeding data after intrauterine device insertion.

Authors:  Siripanth Nippita; Johana D Oviedo; Margarita G Velasco; Carolyn L Westhoff; Anne R Davis; Paula M Castaño
Journal:  Contraception       Date:  2015-09-09       Impact factor: 3.375

9.  Contraceptive Method Uptake at Title X Health Centers in Utah.

Authors:  Corinne D Sexsmith; Jessica N Sanders; Rebecca G Simmons; Cristen Dalessandro; David K Turok
Journal:  Womens Health Issues       Date:  2021-03-06

10.  Provider Attitudes, Preferences, and Practices Regarding Sexual and Reproductive Health for Adolescents and Young Adults With Sickle Cell Disease.

Authors:  Maayan Leroy-Melamed; Seethal Jacob; Marcia L Shew; Traci M Kazmerski
Journal:  J Adolesc Health       Date:  2021-07-20       Impact factor: 5.012

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