BACKGROUND AND OBJECTIVE: To compare images of geographic atrophy (GA) obtained using spectral domain optical coherence tomography (SD-OCT) with images obtained using fundus autofluorescence (FAF). PATIENTS AND METHODS: Five eyes from patients with dry AMD were imaged using SD-OCT and FAF, and the size and shape of the GA were compared. RESULTS: GA appears bright on SD-OCT compared with the surrounding areas with an intact retinal pigment epithelium because of increased reflectivity from the underlying choroid. SD-OCT and FAF both identified GA reproducibly, and measurement of the area of GA is comparable between the two methods with a mean difference of 2.7% of the total area. CONCLUSION: SD-OCT can identify and quantitate areas of GA. The size and shape of these areas correlate well to the areas of GA seen on autofluorescence images; however, SD-OCT imaging also provides important cross-sectional anatomic information.
BACKGROUND AND OBJECTIVE: To compare images of geographic atrophy (GA) obtained using spectral domain optical coherence tomography (SD-OCT) with images obtained using fundus autofluorescence (FAF). PATIENTS AND METHODS: Five eyes from patients with dry AMD were imaged using SD-OCT and FAF, and the size and shape of the GA were compared. RESULTS: GA appears bright on SD-OCT compared with the surrounding areas with an intact retinal pigment epithelium because of increased reflectivity from the underlying choroid. SD-OCT and FAF both identified GA reproducibly, and measurement of the area of GA is comparable between the two methods with a mean difference of 2.7% of the total area. CONCLUSION: SD-OCT can identify and quantitate areas of GA. The size and shape of these areas correlate well to the areas of GA seen on autofluorescence images; however, SD-OCT imaging also provides important cross-sectional anatomic information.
Authors: M Fleckenstein; U Wolf-Schnurrbusch; S Wolf; C von Strachwitz; F G Holz; S Schmitz-Valckenberg Journal: Ophthalmologe Date: 2010-11 Impact factor: 1.059
Authors: Christian Ahlers; Erich Götzinger; Michael Pircher; Isabelle Golbaz; Franz Prager; Christopher Schütze; Bernhard Baumann; Christoph K Hitzenberger; Ursula Schmidt-Erfurth Journal: Invest Ophthalmol Vis Sci Date: 2009-09-24 Impact factor: 4.799
Authors: Yingying Shi; Zhongdi Chu; Liang Wang; Qinqin Zhang; William Feuer; Luis de Sisternes; Mary K Durbin; Giovanni Gregori; Ruikang K Wang; Philip J Rosenfeld Journal: Am J Ophthalmol Date: 2020-07-02 Impact factor: 5.258
Authors: Monika Fleckenstein; Steffen Schmitz-Valckenberg; Christine Martens; Sebastian Kosanetzky; Christian K Brinkmann; Gregory S Hageman; Frank G Holz Journal: Invest Ophthalmol Vis Sci Date: 2011-06-01 Impact factor: 4.799