Literature DB >> 19317827

The metabolic syndrome: in need of a global mission statement.

A J Cameron1, P Z Zimmet, J E Shaw, K G M M Alberti.   

Abstract

AIMS: The value of clinical definitions of the metabolic syndrome has been questioned, with confusion surrounding their intended use and purpose. Our aim was to construct a mission statement that outlines the value of the metabolic syndrome in clinical and public health settings.
METHODS: Case studies have been used to demonstrate three key points.
RESULTS: We argue here for recognition of obesity as being a crucial element within the metabolic syndrome but perhaps even more important before its development. We also contend that the concept does indeed have a role as a risk prediction tool, and that it could provide a useful metric for the scale and progress of the looming global epidemic of diabetes and cardiovascular disease.
CONCLUSIONS: Through appreciation of its purpose, and recognition of both its limitations and those attributes that make it unique and valuable, we believe we have demonstrated here that the metabolic syndrome deserves its place in the global toolbox of diabetes and CVD prevention.

Entities:  

Mesh:

Year:  2009        PMID: 19317827     DOI: 10.1111/j.1464-5491.2009.02681.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  18 in total

1.  From evidence to practice: consensus in cardiovascular risk assessment and diabetes.

Authors:  Michael Crooke
Journal:  Clin Biochem Rev       Date:  2009-11

2.  The metabolic syndrome: what's in a name?

Authors:  Glenn Matfin
Journal:  Ther Adv Endocrinol Metab       Date:  2010-04       Impact factor: 3.565

3.  Amerindians show no association of PPAR-γ2 gene Ala12 allele and obesity: an "unthrifty" variant population genetics.

Authors:  Antonio Arnaiz-Villena; Mercedes Fernández-Honrado; Cristina Areces; Mercedes Enríquez-de-Salamanca; Sedeka Abd-El-Fatah-Khalil; Carmen Coca; Ignacio Arribas; Manuel Algora; Diego Rey
Journal:  Mol Biol Rep       Date:  2012-10-25       Impact factor: 2.316

4.  Amerindians show no association of PC-1 gene Gln121 allele and obesity: a thrifty gene population genetics.

Authors:  Diego Rey; Mercedes Fernandez-Honrado; Cristina Areces; Manuel Algora; Sedeka Abd-El-Fatah-Khalil; Mercedes Enriquez-de-Salamanca; Carmen Coca; Ignacio Arribas; Antonio Arnaiz-Villena
Journal:  Mol Biol Rep       Date:  2012-02-12       Impact factor: 2.316

5.  Effect of HDL composition and particle size on the resistance of HDL to the oxidation.

Authors:  Nakanishi Shuhei; Sanni Söderlund; Matti Jauhiainen; Marja-Riitta Taskinen
Journal:  Lipids Health Dis       Date:  2010-09-23       Impact factor: 3.876

6.  Metabolic syndrome predicts vascular changes in whole body magnetic resonance imaging in patients with long standing diabetes mellitus.

Authors:  Hannes M Findeisen; Sabine Weckbach; Renée G Stark; Maximilian F Reiser; Stefan O Schoenberg; Klaus G Parhofer
Journal:  Cardiovasc Diabetol       Date:  2010-08-30       Impact factor: 9.951

7.  Metabolic syndrome in estonia: prevalence and associations with insulin resistance.

Authors:  Triin Eglit; Tarvo Rajasalu; Margus Lember
Journal:  Int J Endocrinol       Date:  2012-02-25       Impact factor: 3.257

Review 8.  Arginase as a Critical Prooxidant Mediator in the Binomial Endothelial Dysfunction-Atherosclerosis.

Authors:  Luiza A Rabelo; Fernanda O Ferreira; Valéria Nunes-Souza; Lucas José Sá da Fonseca; Marília O F Goulart
Journal:  Oxid Med Cell Longev       Date:  2015-05-04       Impact factor: 6.543

9.  Associations between resident perceptions of the local residential environment and metabolic syndrome.

Authors:  Katherine Baldock; Catherine Paquet; Natasha Howard; Neil Coffee; Graeme Hugo; Anne Taylor; Robert Adams; Mark Daniel
Journal:  J Environ Public Health       Date:  2012-09-25

10.  Use of CHAID decision trees to formulate pathways for the early detection of metabolic syndrome in young adults.

Authors:  Brian Miller; Mark Fridline; Pei-Yang Liu; Deborah Marino
Journal:  Comput Math Methods Med       Date:  2014-04-10       Impact factor: 2.238

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