Literature DB >> 19300884

Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer's disease: the ALZHEMED (Tramiprosate) experience.

D Saumier1, P S Aisen, S Gauthier, B Vellas, S H Ferris, A Duong, J Suhy, J Oh, W Lau, D Garceau, D Haine, J Sampalis.   

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Year:  2009        PMID： 19300884     DOI： 10.1007/s12603-009-0047-4

Source DB:  PubMed          Journal:  J Nutr Health Aging        ISSN： 1279-7707            Impact factor:   4.075


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  21 in total

1.  A quantitative MR study of the hippocampal formation, the amygdala, and the temporal horn of the lateral ventricle in healthy subjects 40 to 90 years of age.

Authors:  Q Mu; J Xie; Z Wen; Y Weng; Z Shuyun
Journal:  AJNR Am J Neuroradiol       Date:  1999-02       Impact factor: 3.825

Review 2.  Biomarkers and surrogate markers: an FDA perspective.

Authors:  Russell Katz
Journal:  NeuroRx       Date:  2004-04

Review 3.  The role of biomarkers in clinical trials for Alzheimer disease.

Authors:  Leon J Thal; Kejal Kantarci; Eric M Reiman; William E Klunk; Michael W Weiner; Henrik Zetterberg; Douglas Galasko; Domenico Praticò; Sue Griffin; Dale Schenk; Eric Siemers
Journal:  Alzheimer Dis Assoc Disord       Date:  2006 Jan-Mar       Impact factor: 2.703

4.  Hippocampal atrophy in early Alzheimer's disease: anatomic specificity and validation.

Authors:  A Convit; M J de Leon; J Golomb; A E George; C Y Tarshish; M Bobinski; W Tsui; S De Santi; J Wegiel; H Wisniewski
Journal:  Psychiatr Q       Date:  1993

5.  Hippocampal atrophy in persons with age-associated memory impairment: volumetry within a common space.

Authors:  Michael S Mega; Gary W Small; Mina L Xu; Jenaro Felix; Mario Manese; Nha P Tran; Jason I Dailey; Linda M Ercoli; Susan Y Bookheimer; Arthur W Toga
Journal:  Psychosom Med       Date:  2002 May-Jun       Impact factor: 4.312

6.  A Phase II study targeting amyloid-beta with 3APS in mild-to-moderate Alzheimer disease.

Authors:  P S Aisen; D Saumier; R Briand; J Laurin; F Gervais; P Tremblay; D Garceau
Journal:  Neurology       Date:  2006-11-02       Impact factor: 9.910

7.  MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease.

Authors:  B C Dickerson; I Goncharova; M P Sullivan; C Forchetti; R S Wilson; D A Bennett; L A Beckett; L deToledo-Morrell
Journal:  Neurobiol Aging       Date:  2001 Sep-Oct       Impact factor: 4.673

8.  Comparison of automated and manual MRI volumetry of hippocampus in normal aging and dementia.

Authors:  Yuan-Yu Hsu; Norbert Schuff; An-Tao Du; Kevin Mark; Xiaoping Zhu; Dawn Hardin; Michael W Weiner
Journal:  J Magn Reson Imaging       Date:  2002-09       Impact factor: 4.813

9.  Volumes of hippocampus, amygdala and frontal lobes in the MRI-based diagnosis of early Alzheimer's disease: correlation with memory functions.

Authors:  M P Laakso; H Soininen; K Partanen; E L Helkala; P Hartikainen; P Vainio; M Hallikainen; T Hänninen; P J Riekkinen
Journal:  J Neural Transm Park Dis Dement Sect       Date:  1995

Review 10.  Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress.

Authors:  Laura Canevari; Andrey Y Abramov; Michael R Duchen
Journal:  Neurochem Res       Date:  2004-03       Impact factor: 3.996
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  12 in total

Review 1.  Quantitative structural MRI for early detection of Alzheimer's disease.

Authors:  Linda K McEvoy; James B Brewer
Journal:  Expert Rev Neurother       Date:  2010-11       Impact factor: 4.618

Review 2.  Biomarkers for Alzheimer's disease: academic, industry and regulatory perspectives.

Authors:  Harald Hampel; Richard Frank; Karl Broich; Stefan J Teipel; Russell G Katz; John Hardy; Karl Herholz; Arun L W Bokde; Frank Jessen; Yvonne C Hoessler; Wendy R Sanhai; Henrik Zetterberg; Janet Woodcock; Kaj Blennow
Journal:  Nat Rev Drug Discov       Date:  2010-07       Impact factor: 84.694

3.  Imaging and biomarkers will be used for detection and monitoring progression of early Alzheimer's disease.

Authors:  M W Weiner
Journal:  J Nutr Health Aging       Date:  2009-04       Impact factor: 4.075

4.  Editorial: can we improve care for patients with dementia?

Authors:  J E Morley
Journal:  J Nutr Health Aging       Date:  2011-08       Impact factor: 4.075

5.  Amyloid beta (Aβ) peptide modulators and other current treatment strategies for Alzheimer's disease (AD).

Authors:  Walter J Lukiw
Journal:  Expert Opin Emerg Drugs       Date:  2012-03-23       Impact factor: 4.191

Review 6.  The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement.

Authors:  Michael W Weiner; Dallas P Veitch; Paul S Aisen; Laurel A Beckett; Nigel J Cairns; Robert C Green; Danielle Harvey; Clifford R Jack; William Jagust; John C Morris; Ronald C Petersen; Jennifer Salazar; Andrew J Saykin; Leslie M Shaw; Arthur W Toga; John Q Trojanowski
Journal:  Alzheimers Dement       Date:  2016-12-05       Impact factor: 21.566

7.  Use of biomarkers in Alzheimer's trials.

Authors:  B Vellas
Journal:  J Nutr Health Aging       Date:  2009-04       Impact factor: 4.075

Review 8.  Current treatment and recent clinical research in Alzheimer's disease.

Authors:  Judith Neugroschl; Mary Sano
Journal:  Mt Sinai J Med       Date:  2010 Jan-Feb

Review 9.  Anti-Alzheimer's Molecules Derived from Marine Life: Understanding Molecular Mechanisms and Therapeutic Potential.

Authors:  Md Tanvir Kabir; Md Sahab Uddin; Philippe Jeandet; Talha Bin Emran; Saikat Mitra; Ghadeer M Albadrani; Amany A Sayed; Mohamed M Abdel-Daim; Jesus Simal-Gandara
Journal:  Mar Drugs       Date:  2021-04-28       Impact factor: 5.118

10.  Tramiprosate in mild-to-moderate Alzheimer's disease - a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study).

Authors:  Paul S Aisen; Serge Gauthier; Steven H Ferris; Daniel Saumier; Denis Haine; Denis Garceau; Anh Duong; Joyce Suhy; Joonmi Oh; Wan C Lau; John Sampalis
Journal:  Arch Med Sci       Date:  2011-03-08       Impact factor: 3.318
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