Literature DB >> 19295461

False-negative Histoplasma antigen in acute pulmonary histoplasmosis: the value of urinary concentration by ultrafiltration and heat denaturation of serum proteins in detection of Histoplasma antigen.

Ashok Srinivasan1, Martin B Kleiman, Larisa Debelenko, Dennis C Stokes, John De Vincenzo, Joseph L Wheat.   

Abstract

We report an infant with localized pulmonary histoplasmosis in whom Histoplasma antibody assays, quantitative Histoplasma urine and serum antigen concentrations, and histopathologic findings of a mediastinal mass were nondiagnostic. A provisional diagnosis of histoplasmosis was established by using laboratory methods that increase the sensitivity of the antigen assay using ultrafiltration of urine and ethylenediaminetetraacetic acid/heat denaturation of serum proteins.

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Year:  2009        PMID： 19295461      PMCID： PMC5702545          DOI： 10.1097/INF.0b013e318193ecc1

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  10 in total

Review 1.  Improvements in diagnosis of histoplasmosis.

Authors:  L Joseph Wheat
Journal:  Expert Opin Biol Ther       Date:  2006-11       Impact factor: 4.388

2.  Detection of histoplasma antigen by a quantitative enzyme immunoassay.

Authors:  Patricia A Connolly; Michelle M Durkin; Ann M Lemonte; Emily J Hackett; L Joseph Wheat
Journal:  Clin Vaccine Immunol       Date:  2007-10-03

3.  Detection of Histoplasma capsulatum antigenuria by ultrafiltration of samples with false-negative results.

Authors:  Lindsey Egan; Patricia A Connolly; Deanna Fuller; Thomas E Davis; John Witt; Kenneth S Knox; Chadi A Hage; L Joseph Wheat
Journal:  Clin Vaccine Immunol       Date:  2008-02-27

Review 4.  Disseminated histoplasmosis of infancy.

Authors:  R J Leggiadro; F F Barrett; W T Hughes
Journal:  Pediatr Infect Dis J       Date:  1988-11       Impact factor: 2.129

5.  A large urban outbreak of histoplasmosis: clinical features.

Authors:  L J Wheat; T G Slama; H E Eitzen; R B Kohler; M L French; J L Biesecker
Journal:  Ann Intern Med       Date:  1981-03       Impact factor: 25.391

6.  Differentiation of lymphoma from histoplasmosis in children with mediastinal masses.

Authors:  J W Gaebler; M B Kleiman; M Cohen; M L French; J L Grosfeld; T R Weber; R Weetman
Journal:  J Pediatr       Date:  1984-05       Impact factor: 4.406

7.  Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America.

Authors:  L Joseph Wheat; Alison G Freifeld; Martin B Kleiman; John W Baddley; David S McKinsey; James E Loyd; Carol A Kauffman
Journal:  Clin Infect Dis       Date:  2007-08-27       Impact factor: 9.079

8.  Diagnosis of histoplasmosis by antigen detection during an outbreak in Indianapolis, Ind.

Authors:  B Williams; M Fojtasek; P Connolly-Stringfield; J Wheat
Journal:  Arch Pathol Lab Med       Date:  1994-12       Impact factor: 5.534

9.  Diagnosis of disseminated histoplasmosis by detection of Histoplasma capsulatum antigen in serum and urine specimens.

Authors:  L J Wheat; R B Kohler; R P Tewari
Journal:  N Engl J Med       Date:  1986-01-09       Impact factor: 91.245

10.  Unusual manifestations of histoplasmosis in childhood.

Authors:  G A Weinberg; M B Kleiman; J L Grosfeld; T R Weber; L J Wheat
Journal:  Pediatrics       Date:  1983-07       Impact factor: 7.124
  10 in total
  4 in total

Review 1.  Paediatric Histoplasmosis 2000-2019: A Review of 83 Cases.

Authors:  Rebecca MacInnes; Adilia Warris
Journal:  J Fungi (Basel)       Date:  2021-06-04

2.  Antigen negative gastrointestinal histoplasmosis in an AIDS patient.

Authors:  Betsy Escobar; Victoria N Maldonado; Sofia Ansari; Juan C Sarria
Journal:  Am J Case Rep       Date:  2014-02-26

Review 3.  Future Directions for Clinical Respiratory Fungal Research.

Authors:  Darius Armstrong-James
Journal:  Mycopathologia       Date:  2021-09-29       Impact factor: 2.574

4.  Urine as a specimen to diagnose infections in twenty-first century: focus on analytical accuracy.

Authors:  Tamara Tuuminen
Journal:  Front Immunol       Date:  2012-03-23       Impact factor: 7.561
  4 in total

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