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Literature DB >> 19278901

Clinical trials for prion disease: difficult challenges, but hope for the future.

Michael D Geschwind.

Abstract

Entities: Chemical Disease Species

Mesh：

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Year: 2009 PMID： 19278901 PMCID： PMC2757050 DOI： 10.1016/S1474-4422(09)70050-X

Source DB: PubMed Journal: Lancet Neurol ISSN： 1474-4422 Impact factor: 44.182

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8 in total

Review 1. Shattuck lecture--neurodegenerative diseases and prions.

Authors: S B Prusiner
Journal: N Engl J Med Date: 2001-05-17 Impact factor: 91.245

2. Quinacrine effects on the central nervous system.

Authors: G L Engel
Journal: JAMA Date: 1966-08-08 Impact factor: 56.272

3. Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease.

Authors: C Korth; B C May; F E Cohen; S B Prusiner
Journal: Proc Natl Acad Sci U S A Date: 2001-08-14 Impact factor: 11.205

4. Compassionate use of quinacrine in Creutzfeldt-Jakob disease fails to show significant effects.

Authors: S Haïk; J P Brandel; D Salomon; V Sazdovitch; N Delasnerie-Lauprêtre; J L Laplanche; B A Faucheux; C Soubrié; E Boher; C Belorgey; J J Hauw; A Alpérovitch
Journal: Neurology Date: 2004-12-28 Impact factor: 9.910

5. Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study.

Authors: M Otto; L Cepek; P Ratzka; S Doehlinger; I Boekhoff; J Wiltfang; E Irle; G Pergande; B Ellers-Lenz; O Windl; H A Kretzschmar; S Poser; H Prange
Journal: Neurology Date: 2004-03-09 Impact factor: 9.910

6. Results of quinacrine administration to patients with Creutzfeldt-Jakob disease.

Authors: Masashi Nakajima; Tatsuo Yamada; Tomohiko Kusuhara; Hisako Furukawa; Mitsuo Takahashi; Atsushi Yamauchi; Yasufumi Kataoka
Journal: Dement Geriatr Cogn Disord Date: 2004-01-20 Impact factor: 2.959

Review 7. A systematic review of prion therapeutics in experimental models.

Authors: Clare R Trevitt; John Collinge
Journal: Brain Date: 2006-07-01 Impact factor: 13.501

8. Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial.

Authors: John Collinge; Michele Gorham; Fleur Hudson; Angus Kennedy; Geraldine Keogh; Suvankar Pal; Martin Rossor; Peter Rudge; Durre Siddique; Moira Spyer; Dafydd Thomas; Sarah Walker; Tom Webb; Steve Wroe; Janet Darbyshire
Journal: Lancet Neurol Date: 2009-03-09 Impact factor: 44.182

8 in total

13 in total

Review 1. Translational research in neurology: dementia.

Authors: Lawrence S Honig
Journal: Arch Neurol Date: 2012-08

2. In vitro neutralization of prions with PrP(Sc)-specific antibodies.

Authors: Ryan Taschuk; Jacques Van der Merwe; Kristen Marciniuk; Andrew Potter; Neil Cashman; Philip Griebel; Scott Napper
Journal: Prion Date: 2015 Impact factor: 3.931

3. Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease.

Authors: Michael D Geschwind; Amy L Kuo; Katherine S Wong; Aissa Haman; Gillian Devereux; Benjamin J Raudabaugh; David Y Johnson; Charles C Torres-Chae; Ron Finley; Paul Garcia; Julie N Thai; Hugo Q Cheng; John M Neuhaus; Sven A Forner; Jacque L Duncan; Katherine L Possin; Stephen J Dearmond; Stanley B Prusiner; Bruce L Miller
Journal: Neurology Date: 2013-10-11 Impact factor: 9.910

4. Differential diagnosis of Jakob-Creutzfeldt disease.

Authors: Ross W Paterson; Charles C Torres-Chae; Amy L Kuo; Tim Ando; Elizabeth A Nguyen; Katherine Wong; Stephen J DeArmond; Aissa Haman; Paul Garcia; David Y Johnson; Bruce L Miller; Michael D Geschwind
Journal: Arch Neurol Date: 2012-12

5. Ethics in prion disease.

Authors: Kendra Bechtel; Michael D Geschwind
Journal: Prog Neurobiol Date: 2013-07-29 Impact factor: 11.685

6. Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity.

Authors: Valentina Villa; Michele Tonelli; Stefano Thellung; Alessandro Corsaro; Bruno Tasso; Federica Novelli; Caterina Canu; Albiana Pino; Katia Chiovitti; Domenico Paludi; Claudio Russo; Anna Sparatore; Antonio Aceto; Vito Boido; Fabio Sparatore; Tullio Florio
Journal: Neurotox Res Date: 2010-04-20 Impact factor: 3.911

7. Development of an ultra-rapid diagnostic method based on heart-type fatty acid binding protein levels in the CSF of CJD patients.

Authors: Yuki Matsui; Katsuya Satoh; Kazuo Mutsukura; Takuya Watanabe; Noriyuki Nishida; Hideo Matsuda; Masaichi Sugino; Susumu Shirabe; Katsumi Eguchi; Yasufumi Kataoka
Journal: Cell Mol Neurobiol Date: 2010-05-25 Impact factor: 5.046