Literature DB >> 19276811

Pneumonia in the elderly.

Mateo Cabre1.   

Abstract

PURPOSE OF REVIEW: The aim is to describe recent advances concerning pneumonia in older patients in relation to epidemiology, microbiology, and factors related to severity, treatment, and prevention. This article is a review of recent studies (2007 and 2008) on pneumonia in older people. RECENT
FINDINGS: The incidence of oropharyngeal dysphagia is increasing among older people. Biological markers of prognosis and severity do not normally offer additional relevant information to clinical data. Viral cause is increasingly relevant, and mixed infections are more severe and affect more old people. A new index has been developed (SMART-COP), which complements the existing Pneumonia Severity Index (PSI) and CURB-65 by improving identification of patients who require intensive care and vasopressor drugs. Reduction in antibiotic treatment duration is not associated with greater mortality or more readmissions. New developments regarding prevention of aspiration pneumonia and the utility of influenza and pneumococcal vaccines are discussed.
SUMMARY: Pneumonia is increasingly caused by viral pathogens, and the pneumococcal and influenza vaccines may not be as effective as was first published. Recent studies have shown that aspiration is an increasing risk factor for pneumonia among older people.

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Year:  2009        PMID: 19276811     DOI: 10.1097/MCP.0b013e328326f571

Source DB:  PubMed          Journal:  Curr Opin Pulm Med        ISSN: 1070-5287            Impact factor:   3.155


  13 in total

1.  The impact of global budgeting on health service utilization, health care expenditures, and quality of care among patients with pneumonia in Taiwan.

Authors:  C-Y Lin; T Ma; C-C Lin; C-H Kao
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2015-12-02       Impact factor: 3.267

2.  Characterization of mutants deficient in the L,D-carboxypeptidase (DacB) and WalRK (VicRK) regulon, involved in peptidoglycan maturation of Streptococcus pneumoniae serotype 2 strain D39.

Authors:  Skye M Barendt; Lok-To Sham; Malcolm E Winkler
Journal:  J Bacteriol       Date:  2011-03-04       Impact factor: 3.490

3.  TLR-2 independent recognition of Mycobacterium tuberculosis by CD11c+ pulmonary cells from old mice.

Authors:  Erin K Rottinghaus; Bridget Vesosky; Joanne Turner
Journal:  Mech Ageing Dev       Date:  2010-06-08       Impact factor: 5.432

4.  Aerosol vaccination induces robust protective immunity to homologous and heterologous influenza infection in mice.

Authors:  Jennifer Humberd Smith; Paula Brooks; Scott Johnson; S Mark Tompkins; Koren M Custer; Debra L Haas; Raydel Mair; Mark Papania; Ralph A Tripp
Journal:  Vaccine       Date:  2011-02-05       Impact factor: 3.641

5.  Instability of ackA (acetate kinase) mutations and their effects on acetyl phosphate and ATP amounts in Streptococcus pneumoniae D39.

Authors:  Smirla Ramos-Montañez; Krystyna M Kazmierczak; Kristy L Hentchel; Malcolm E Winkler
Journal:  J Bacteriol       Date:  2010-10-15       Impact factor: 3.490

6.  Macrophages from elders are more permissive to intracellular multiplication of Mycobacterium tuberculosis.

Authors:  José M Guerra-Laso; Sandra González-García; Carolina González-Cortés; Cristina Diez-Tascón; Ramiro López-Medrano; Octavio M Rivero-Lezcano
Journal:  Age (Dordr)       Date:  2012-07-12

Review 7.  The complication of coinfection.

Authors:  Lesley Pasman
Journal:  Yale J Biol Med       Date:  2012-03-29

8.  Comparison of clinical characteristics and outcomes between aspiration pneumonia and community-acquired pneumonia in patients with chronic obstructive pulmonary disease.

Authors:  Yasuhiro Yamauchi; Hideo Yasunaga; Hiroki Matsui; Wakae Hasegawa; Taisuke Jo; Kazutaka Takami; Kiyohide Fushimi; Takahide Nagase
Journal:  BMC Pulm Med       Date:  2015-07-08       Impact factor: 3.317

Review 9.  Modulation of bacterial pathogenesis by oppressive aging factors: insights into host-pneumococcal interaction strategies.

Authors:  Pooja Shivshankar
Journal:  ISRN Inflamm       Date:  2012-05-17

10.  Aging of the CD4 T Cell Compartment.

Authors:  Julie S Lefebvre; Laura Haynes
Journal:  Open Longev Sci       Date:  2012-01-01
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