Literature DB >> 19276540

A potential role for alterations of zinc and zinc transport proteins in the progression of Alzheimer's disease.

Mark A Lovell1.   

Abstract

Although multiple studies have suggested a role for alterations of zinc (Zn) and zinc transport (ZnT) proteins in the pathogenesis of Alzheimer's disease, the exact role of this essential trace element in the progression of the disease remains unclear. The following review discusses the normal role of Zn and ZnT proteins in brain and the potential effects of their alteration in the pathogenesis of Alzheimer's disease, particularly in the processing of the amyloid-beta protein precursor and amyloid-beta peptide generation and aggregation.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19276540      PMCID： PMC2881701          DOI： 10.3233/JAD-2009-0992

Source DB:  PubMed          Journal:  J Alzheimers Dis        ISSN： 1387-2877            Impact factor:   4.472


  199 in total

Review 1.  Alzheimer's disease and the amyloid cascade hypothesis: ten years on.

Authors:  Bernd Sommer
Journal:  Curr Opin Pharmacol       Date:  2002-02       Impact factor: 5.547

2.  Purification and cloning of amyloid precursor protein beta-secretase from human brain.

Authors:  S Sinha; J P Anderson; R Barbour; G S Basi; R Caccavello; D Davis; M Doan; H F Dovey; N Frigon; J Hong; K Jacobson-Croak; N Jewett; P Keim; J Knops; I Lieberburg; M Power; H Tan; G Tatsuno; J Tung; D Schenk; P Seubert; S M Suomensaari; S Wang; D Walker; J Zhao; L McConlogue; V John
Journal:  Nature       Date:  1999-12-02       Impact factor: 49.962

3.  Determination of main and trace element contents in human brain by NAA and ICP-AES methods.

Authors:  E Andrási; J Nádasdi; Z Molnar; L Bezur; L Ernyei
Journal:  Biol Trace Elem Res       Date:  1990 Jul-Dec       Impact factor: 3.738

4.  Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

Authors:  J Lewis; D W Dickson; W L Lin; L Chisholm; A Corral; G Jones; S H Yen; N Sahara; L Skipper; D Yager; C Eckman; J Hardy; M Hutton; E McGowan
Journal:  Science       Date:  2001-08-24       Impact factor: 47.728

5.  Family-based association between Alzheimer's disease and variants in UBQLN1.

Authors:  Lars Bertram; Mikko Hiltunen; Michele Parkinson; Martin Ingelsson; Christoph Lange; Karunya Ramasamy; Kristina Mullin; Rashmi Menon; Andrew J Sampson; Monica Y Hsiao; Kathryn J Elliott; Gonül Velicelebi; Thomas Moscarillo; Bradley T Hyman; Steven L Wagner; K David Becker; Deborah Blacker; Rudolph E Tanzi
Journal:  N Engl J Med       Date:  2005-03-03       Impact factor: 91.245

6.  Modulating amyloid self-assembly and fibril morphology with Zn(II).

Authors:  Jijun Dong; Jacob E Shokes; Robert A Scott; David G Lynn
Journal:  J Am Chem Soc       Date:  2006-03-22       Impact factor: 15.419

Review 7.  Common mechanisms of amyloid oligomer pathogenesis in degenerative disease.

Authors:  Charles G Glabe
Journal:  Neurobiol Aging       Date:  2006-02-14       Impact factor: 4.673

8.  Aggregation and metal-binding properties of mutant forms of the amyloid A beta peptide of Alzheimer's disease.

Authors:  A Clements; D Allsop; D M Walsh; C H Williams
Journal:  J Neurochem       Date:  1996-02       Impact factor: 5.372

9.  Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes.

Authors:  Ayae Kinoshita; Hiroaki Fukumoto; Tejal Shah; Christa M Whelan; Michael C Irizarry; Bradley T Hyman
Journal:  J Cell Sci       Date:  2003-06-26       Impact factor: 5.285

10.  Brain Iron and Zinc Contents of German Patients with Alzheimer Disease.

Authors:  Erzsébet Andrási; Eva Farkas; Dieter Gawlik; Ullrich Rösick; Peter Brätter
Journal:  J Alzheimers Dis       Date:  2000-03       Impact factor: 4.472
View more
  24 in total

1.  Selective, quantitative measurement of releasable synaptic zinc in human autopsy hippocampal brain tissue from Alzheimer's disease patients.

Authors:  Nicole L Bjorklund; V-M Sadagoparamanujam; Giulio Taglialatela
Journal:  J Neurosci Methods       Date:  2011-09-16       Impact factor: 2.390

Review 2.  Therapeutic targets in age-related macular disease.

Authors:  Alan C Bird
Journal:  J Clin Invest       Date:  2010-09-01       Impact factor: 14.808

Review 3.  A potential role for zinc alterations in the pathogenesis of Alzheimer's disease.

Authors:  Ganna Lyubartseva; Mark A Lovell
Journal:  Biofactors       Date:  2012-03-23       Impact factor: 6.113

Review 4.  Zinc in the central nervous system: From molecules to behavior.

Authors:  Shannon D Gower-Winter; Cathy W Levenson
Journal:  Biofactors       Date:  2012-03-31       Impact factor: 6.113

5.  Supplementation with zinc in rats enhances memory and reverses an age-dependent increase in plasma copper.

Authors:  Leslie A Sandusky-Beltran; Bryce L Manchester; Ewan C McNay
Journal:  Behav Brain Res       Date:  2017-07-08       Impact factor: 3.332

6.  Synergistic accumulation of iron and zinc by cultured astrocytes.

Authors:  Glenda M Bishop; Ivo F Scheiber; Ralf Dringen; Stephen R Robinson
Journal:  J Neural Transm (Vienna)       Date:  2010-06-12       Impact factor: 3.575

Review 7.  Metal ion physiopathology in neurodegenerative disorders.

Authors:  Silvia Bolognin; Luigi Messori; Paolo Zatta
Journal:  Neuromolecular Med       Date:  2009-11-28       Impact factor: 3.843

8.  ZIP4 is a novel molecular marker for glioma.

Authors:  Yi Lin; Yong Chen; Yongzhi Wang; Jingxuan Yang; Vivian F Zhu; Yulun Liu; Xiaobo Cui; Leon Chen; Wei Yan; Tao Jiang; Georgene W Hergenroeder; Stephen A Fletcher; Jonathan M Levine; Dong H Kim; Nitin Tandon; Jay-Jiguang Zhu; Min Li
Journal:  Neuro Oncol       Date:  2013-04-17       Impact factor: 12.300

9.  Absence of amyloid β oligomers at the postsynapse and regulated synaptic Zn2+ in cognitively intact aged individuals with Alzheimer's disease neuropathology.

Authors:  Nicole L Bjorklund; Lindsay C Reese; V-M Sadagoparamanujam; Valeria Ghirardi; Randall L Woltjer; Giulio Taglialatela
Journal:  Mol Neurodegener       Date:  2012-05-28       Impact factor: 14.195

10.  Genome-wide association study identifies loci affecting blood copper, selenium and zinc.

Authors:  David M Evans; Gu Zhu; Veronica Dy; Andrew C Heath; Pamela A F Madden; John P Kemp; George McMahon; Beate St Pourcain; Nicholas J Timpson; Jean Golding; Debbie A Lawlor; Colin Steer; Grant W Montgomery; Nicholas G Martin; George Davey Smith; John B Whitfield
Journal:  Hum Mol Genet       Date:  2013-05-29       Impact factor: 6.150
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.