Literature DB >> 19273540

Use of a strategy based on calculated risk scores in managing cardiovascular risk factors in a large British cohort of patients with systemic lupus erythematosus.

Sean G O'Neill1, Jose M Pego-Reigosa, Aroon D Hingorani, Rupa Bessant, David A Isenberg, Anisur Rahman.   

Abstract

OBJECTIVE: To develop a strategy for stratifying risk of cardiovascular disease (CVD) in a cohort of patients with SLE and to test the usefulness of this strategy in rationalizing management of cardiovascular risk factors.
METHODS: For each patient, data were collected once each year to allow calculation of risk of developing CVD in the next 10 years. Those with risk values >7.5% were considered for intervention to reduce risk. The risk figures and effect of this strategy on management of the cohort as a whole were assessed after 3 years. Patients who had been identified as smokers in 2005 were contacted in 2008 to assess changes in their smoking behaviour.
RESULTS: Over 3 years, 308 patients (>90%) of the cohort had CVD risk assessed at least once. Although 10-year CVD risk exceeded 7.5% in 35 patients, the majority (24) of these had either diabetes mellitus or previous CVD for which established cardiovascular risk reduction protocols already exist. Calculation of risk scores did not alter management in 96.5% of the patients. Ninety percent of the smokers remembered being counselled about smoking in the lupus clinic, 70% had received help to reduce smoking and 47% had either reduced or stopped.
CONCLUSION: A protocol mandating regular assessment of cardiovascular risk factors in our lupus clinic resulted in this issue being discussed with >90% of the patients and there was some evidence of an impact on smoking. However, use of these factors to calculate 10-year risk scores did not alter management in over 96% of the cases.

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Year:  2009        PMID: 19273540     DOI: 10.1093/rheumatology/kep037

Source DB:  PubMed          Journal:  Rheumatology (Oxford)        ISSN: 1462-0324            Impact factor:   7.580


  10 in total

1.  Patient Perspectives on Smoking Cessation and Interventions in Rheumatology Clinics.

Authors:  Aimée Wattiaux; Brittany Bettendorf; Laura Block; Andrea Gilmore-Bykovskyi; Edmond Ramly; Megan E Piper; Ann Rosenthal; Jane Sadusky; Elizabeth Cox; Betty Chewning; Christie M Bartels
Journal:  Arthritis Care Res (Hoboken)       Date:  2020-03       Impact factor: 4.794

2.  Cardiovascular Disease Prevention Counseling Program for Systemic Lupus Erythematosus Patients.

Authors:  Cécile M Yelnik; Monica Richey; Virginia Haiduc; Sotiria Everett; Meng Zhang; Doruk Erkan
Journal:  Arthritis Care Res (Hoboken)       Date:  2017-06-26       Impact factor: 4.794

Review 3.  Why are kids with lupus at an increased risk of cardiovascular disease?

Authors:  Catherine Quinlan; Stephen D Marks; Kjell Tullus
Journal:  Pediatr Nephrol       Date:  2015-09-23       Impact factor: 3.714

4.  Results of a specific smoking cessation program for patients with arthritis in a rheumatology clinic.

Authors:  Antonio Naranjo; Ana Bilbao; Celia Erausquin; Soledad Ojeda; Félix M Francisco; Iñigo Rúa-Figueroa; Carlos Rodríguez-Lozano
Journal:  Rheumatol Int       Date:  2013-09-05       Impact factor: 2.631

5.  Influence of autoimmunity and inflammation on endothelial function and thrombosis in systemic lupus erythematosus patients.

Authors:  Kamil Bugała; Adam Mazurek; Krzysztof Gryga; Monika Komar; Grzegorz Kopeć; Jacek Musiał; Piotr Podolec; Carlo Perricone; Wojciech Płazak
Journal:  Clin Rheumatol       Date:  2018-04-20       Impact factor: 2.980

6.  Cardiorespiratory biomarker responses in healthy young adults to drastic air quality changes surrounding the 2008 Beijing Olympics.

Authors:  Junfeng Zhang; Tong Zhu; Howard Kipen; Guangfa Wang; Wei Huang; David Rich; Ping Zhu; Yuedan Wang; Shou-En Lu; Pamela Ohman-Strickland; Scott Diehl; Min Hu; Jian Tong; Jicheng Gong; Duncan Thomas
Journal:  Res Rep Health Eff Inst       Date:  2013-02

Review 7.  Imaging assessment of cardiovascular disease in systemic lupus erythematosus.

Authors:  Sara C Croca; Anisur Rahman
Journal:  Clin Dev Immunol       Date:  2011-10-23

Review 8.  Echocardiography in Autoimmune Rheumatic Diseases for Diagnosis and Prognosis of Cardiovascular Complications.

Authors:  George Makavos; Maria Varoudi; Konstantina Papangelopoulou; Eirini Kapniari; Panagiotis Plotas; Ignatios Ikonomidis; Evangelia Papadavid
Journal:  Medicina (Kaunas)       Date:  2020-09-01       Impact factor: 2.430

9.  Assessing the validity of QRISK3 in predicting cardiovascular events in systemic lupus erythematosus.

Authors:  Lisa Zhu; Manpreet Singh; Sonia Lele; Lori Sahakian; Jennifer Grossman; Bevra Hahn; Maureen McMahon
Journal:  Lupus Sci Med       Date:  2022-02

Review 10.  Management of cardiovascular disease in patients with systemic lupus erythematosus.

Authors:  Paramarjan Piranavan; Andras Perl
Journal:  Expert Opin Pharmacother       Date:  2020-06-08       Impact factor: 3.889

  10 in total

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