Literature DB >> 19269752

In vitro activity of terbinafine associated to amphotericin B, fluvastatin, rifampicin, metronidazole and ibuprofen against Pythium insidiosum.

Ayrton S Cavalheiro1, Régis A Zanette, Tatiana B Spader, Luciane Lovato, Maria Isabel Azevedo, Sonia Botton, Sydney H Alves, Janio M Santurio.   

Abstract

We evaluated the in vitro activities of terbinafine alone and in combination with amphotericin B, fluvastatin, rifampicin, metronidazole or ibuprofen against 17 clinical isolates of Pythium insidiosum. The assays were based on technique M38-A2, as well as the checkerboard microdilution method. The main synergism observed was by combination of terbinafine plus amphotericin B (41.18%). Antagonisms were observed in combinations of terbinafine with fluvastatin (35.30%) or rifampicin (5.88%).

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Year:  2009        PMID： 19269752     DOI： 10.1016/j.vetmic.2009.01.036

Source DB:  PubMed          Journal:  Vet Microbiol        ISSN： 0378-1135            Impact factor:   3.293


  6 in total

1.  In vitro synergism observed with azithromycin, clarithromycin, minocycline, or tigecycline in association with antifungal agents against Pythium insidiosum.

Authors:  Francielli P K Jesus; Laerte Ferreiro; Érico S Loreto; Maiara B Pilotto; Aline Ludwig; Karine Bizzi; Juliana S M Tondolo; Régis A Zanette; Sydney H Alves; Janio M Santurio
Journal:  Antimicrob Agents Chemother       Date:  2014-07-07       Impact factor: 5.191

2.  New insights into the in vitro susceptibility of Pythium insidiosum.

Authors:  Erico S Loreto; Juliana S M Tondolo; Maiara B Pilotto; Sydney H Alves; Janio M Santurio
Journal:  Antimicrob Agents Chemother       Date:  2014-09-15       Impact factor: 5.191

3.  In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics.

Authors:  Erico Silva Loreto; Débora Alves Nunes Mario; Laura Bedin Denardi; Sydney Hartz Alves; Janio Morais Santurio
Journal:  Antimicrob Agents Chemother       Date:  2011-05-02       Impact factor: 5.191

4.  In Vitro Susceptibility of Pythium insidiosum to Melaleuca alternifolia, Mentha piperita and Origanum vulgare Essential Oils Combinations.

Authors:  Júlia de Souza Silveira Valente; Anelise de Oliveira da Silva Fonseca; Laura Bedin Denardi; Vanessa Silveira Dal Ben; Fernando de Souza Maia Filho; Cristiane Telles Baptista; Caroline Quintana Braga; Cristina Gomes Zambrano; Sydney Hartz Alves; Sônia de Avila Botton; Daniela Isabel Brayer Pereira
Journal:  Mycopathologia       Date:  2016-05-21       Impact factor: 2.574

5.  Pythium keratitis in South India: Incidence, clinical profile, management, and treatment recommendation.

Authors:  Ravula Hasika; Prajna Lalitha; Naveen Radhakrishnan; Gunasekaran Rameshkumar; N Venkatesh Prajna; Muthiah Srinivasan
Journal:  Indian J Ophthalmol       Date:  2019-01       Impact factor: 1.848

Review 6.  Review of methods and antimicrobial agents for susceptibility testing against Pythium insidiosum.

Authors:  Hanna Yolanda; Theerapong Krajaejun
Journal:  Heliyon       Date:  2020-04-12
  6 in total

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