OBJECTIVES/HYPOTHESIS: The purpose of this study is to review our experience with sialendoscopy for the management of radioiodine-induced sialadenitis. METHODS: Retrospective chart review of all patients with radioiodine-induced sialadenitis treated with interventional sialendoscopy. RESULTS: Twelve female patients with a mean age of 46.5 years (range, 25-77 years) underwent interventional sialendoscopy for the treatment of recalcitrant sialadenitis from radioiodine-induced damage to the major salivary glands. Symptoms arising from the parotid gland were seen in 75% of patients, whereas symptoms arising from the submandibular gland were seen in 50%. Three patients (25%) presented symptoms in both the parotids and the submandibular glands. The mean dose of radioiodine was 143 mCi (range, 101.9-185.7 mCi) received as a single dose prior to their referral. The mean duration from radioiodine ablation therapy to sialendoscopy was 10.4 months (range, 5-16 months). Thirty-two glands (20 parotid, 12 submandibular) were taken to the operating room, with complete endoscopy successful in 27 glands (84.4%). Ductal stenosis (30%) and mucus plugs (44%) were the most common types of ductal pathology. Sialendoscopy improved the symptoms in 75% (9/12) of patients, with no serious complications reported in follow-up ranging from 2 weeks to 33 months (median, 6 months). CONCLUSIONS: Interventional sialendoscopy is an effective tool for the management of patients with radioiodine-induced sialadenitis that is unresponsive to medical management.
OBJECTIVES/HYPOTHESIS: The purpose of this study is to review our experience with sialendoscopy for the management of radioiodine-induced sialadenitis. METHODS: Retrospective chart review of all patients with radioiodine-induced sialadenitis treated with interventional sialendoscopy. RESULTS: Twelve female patients with a mean age of 46.5 years (range, 25-77 years) underwent interventional sialendoscopy for the treatment of recalcitrant sialadenitis from radioiodine-induced damage to the major salivary glands. Symptoms arising from the parotid gland were seen in 75% of patients, whereas symptoms arising from the submandibular gland were seen in 50%. Three patients (25%) presented symptoms in both the parotids and the submandibular glands. The mean dose of radioiodine was 143 mCi (range, 101.9-185.7 mCi) received as a single dose prior to their referral. The mean duration from radioiodine ablation therapy to sialendoscopy was 10.4 months (range, 5-16 months). Thirty-two glands (20 parotid, 12 submandibular) were taken to the operating room, with complete endoscopy successful in 27 glands (84.4%). Ductal stenosis (30%) and mucus plugs (44%) were the most common types of ductal pathology. Sialendoscopy improved the symptoms in 75% (9/12) of patients, with no serious complications reported in follow-up ranging from 2 weeks to 33 months (median, 6 months). CONCLUSIONS: Interventional sialendoscopy is an effective tool for the management of patients with radioiodine-induced sialadenitis that is unresponsive to medical management.
Authors: Bryan R Haugen; Erik K Alexander; Keith C Bible; Gerard M Doherty; Susan J Mandel; Yuri E Nikiforov; Furio Pacini; Gregory W Randolph; Anna M Sawka; Martin Schlumberger; Kathryn G Schuff; Steven I Sherman; Julie Ann Sosa; David L Steward; R Michael Tuttle; Leonard Wartofsky Journal: Thyroid Date: 2016-01 Impact factor: 6.568
Authors: Mihir K Bhayani; Varun Acharya; Suchada Kongkiatkamon; Sally Farah; Dianna B Roberts; Jennifer Sterba; Mark S Chambers; Stephen Y Lai Journal: Thyroid Date: 2015-05-15 Impact factor: 6.568
Authors: F Brozzi; T Rago; W Bencivelli; F Bianchi; P Santini; P Vitti; A Pinchera; C Ceccarelli Journal: J Endocrinol Invest Date: 2012-04-05 Impact factor: 4.256
Authors: A Gallo; M Benazzo; P Capaccio; L De Campora; M De Vincentiis; M Fusconi; S Martellucci; G Paludetti; E Pasquini; R Puxeddu; R Speciale Journal: Acta Otorhinolaryngol Ital Date: 2015-10 Impact factor: 2.124