BACKGROUND: Epidemiologic and genetic studies have suggested a bidirectional association between breast carcinoma (BC) and malignant melanoma (MM). OBSERVATION: We present a series of patients with MM and BC detected in our department within a span of 6 months, raising concerns for the high associations between the two malignancies. This led us to match the concordance of the two tumours in the National Irish Cancer Registry. CONCLUSION: The national figures provide evidence of a link between BC and MM. We recommend increased awareness among clinicians leading to more detailed surveillance of both second primary tumours. All MM patients with a family history of BC should be referred to a breast clinic. Women above the age of 40 with MM should undergo annual mammography and those less than 40 may be better evaluated with a breast MRI. All breast cancer patients should be made aware of the significance of changing moles and those with suspicious lesions referred to a dermatologist for evaluation.
BACKGROUND: Epidemiologic and genetic studies have suggested a bidirectional association between breast carcinoma (BC) and malignant melanoma (MM). OBSERVATION: We present a series of patients with MM and BC detected in our department within a span of 6 months, raising concerns for the high associations between the two malignancies. This led us to match the concordance of the two tumours in the National Irish Cancer Registry. CONCLUSION: The national figures provide evidence of a link between BC and MM. We recommend increased awareness among clinicians leading to more detailed surveillance of both second primary tumours. All MM patients with a family history of BC should be referred to a breast clinic. Women above the age of 40 with MM should undergo annual mammography and those less than 40 may be better evaluated with a breast MRI. All breast cancerpatients should be made aware of the significance of changing moles and those with suspicious lesions referred to a dermatologist for evaluation.
Authors: A Borg; T Sandberg; K Nilsson; O Johannsson; M Klinker; A Måsbäck; J Westerdahl; H Olsson; C Ingvar Journal: J Natl Cancer Inst Date: 2000-08-02 Impact factor: 13.506
Authors: T Debniak; B Górski; T Huzarski; T Byrski; C Cybulski; A Mackiewicz; S Gozdecka-Grodecka; J Gronwald; E Kowalska; O Haus; E Grzybowska; M Stawicka; M Swiec; K Urbański; S Niepsuj; B Waśko; S Góźdź; P Wandzel; C Szczylik; D Surdyka; A Rozmiarek; O Zambrano; M Posmyk; S A Narod; J Lubinski Journal: J Med Genet Date: 2005-05-06 Impact factor: 6.318
Authors: Tadeusz Debniak; Bohdan Górski; Rodney J Scott; Cezary Cybulski; Krzysztof Medrek; Elzbieta Zowocka; Grzegorz Kurzawski; Boguslaw Debniak; Józef Kadny; Stanislawa Bielecka-Grzela; Romuald Maleszka; Jan Lubiński Journal: Int J Cancer Date: 2004-07-01 Impact factor: 7.396
Authors: Karina H Goldberg; Ariel C Yin; Archana Mupparapu; Edward P Retzbach; Gary S Goldberg; Catherine F Yang Journal: J Tradit Complement Med Date: 2016-02-23