Literature DB >> 19262427

Dye extrusion technique (DE-TECH): occult retinal break detection with subretinal dye extrusion during vitrectomy for retinal detachment repair.

Roger Wong1, Bhaskar Gupta, G William Aylward, D Alistair H Laidlaw.   

Abstract

OBJECTIVE: To investigate the effectiveness of a new technique for the identification of occult retinal breaks in vitrectomy retinal detachment repair. Dye Extrusion Technique involves injection of sub retinal dye and extrusion through the unidentified breaks using perfluorocarbon liquid.
METHOD: Retrospective case note analysis. MAIN OUTCOME MEASURES: rate of break detection, rate of use of local retinopexy, and short-term gas tamponade alone; SECONDARY OUTCOMES: anatomical success at 3 months with no long-term tamponade, final visual acuity, progression of proliferative vitreoretinopathy.
RESULTS: Thirty-eight percent of eyes had proliferative vitreoretinopathy of grade C1 or worse. Twenty-five percent underwent primary retinal detachment repair surgery. The remainder underwent repeat operations for previously failed surgery. Breaks were found in 89% of eyes and 81% underwent only local retinopexy and gas tamponade. The overall anatomical success rate was 85% (40/47) which included four cases in which the retina was fully attached awaiting removal of silicone oil. No cases had unexplained loss of vision. No progression of proliferative vitreoretinopathy was noted.
CONCLUSIONS: Results suggest that Dye Extrusion Technique may be an effective technique for the identification of occult retinal breaks and may facilitate simple techniques of detachment repair. No evidence of retino-toxicity from the use of trypan blue was found but the study had limited power to detect adverse effects.

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Year:  2009        PMID: 19262427     DOI: 10.1097/IAE.0b013e31819bab72

Source DB:  PubMed          Journal:  Retina        ISSN: 0275-004X            Impact factor:   4.256


  5 in total

1.  Trans-scleral dye injection during vitreous surgery to identify clinically undetectable retinal breaks causing retinal detachment.

Authors:  D Gupta; J Ong; R L Burton
Journal:  Eye (Lond)       Date:  2011-06-03       Impact factor: 3.775

2.  Modified subretinal dye extrusion technique (MORE-DETECH): subretinal diluted trypan blue for detecting occult retinal breaks in retinal detachment after endotamponade removal.

Authors:  Sumeet Khanduja; Subijay Sinha; Varun Gogia; Ashish Kakkar; Rajpal Vohra
Journal:  Int Ophthalmol       Date:  2013-02-14       Impact factor: 2.031

3.  Impact of Vital Dyes on Cell Viability and Transduction Efficiency of AAV Vectors Used in Retinal Gene Therapy Surgery: An In Vitro and In Vivo Analysis.

Authors:  Anna P Salvetti; Maria I Patrício; Alun R Barnard; Harry O Orlans; Doron G Hickey; Robert E MacLaren
Journal:  Transl Vis Sci Technol       Date:  2017-07-10       Impact factor: 3.283

4.  Chromophore-Assisted Retinal Break Detection to Manage Challenging Situations in Retinal Detachment Redo Surgery.

Authors:  Antonio Berarducci; Martina Colasante; Antonio Laborante
Journal:  Case Rep Ophthalmol Med       Date:  2020-11-30

5.  Scleral buckling with a noncontact wide-angle viewing system in the management of retinal detachment with undetected retinal break: a case report.

Authors:  Mihori Kita; Yukiko Fujii; Naoaki Kawagoe; Sachiyo Hama
Journal:  Clin Ophthalmol       Date:  2013-03-21
  5 in total

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