Sarah L Pedersen1, Denis M McCarthy. 1. Department of Psychological Sciences, 210 McAlester Hall, University of Missouri, Columbia, Missouri 65211, USA.
Abstract
OBJECTIVE: Alcohol response is a widely studied risk factor for heavy drinking behavior and alcohol-use disorders. This study examined acute subjective response to alcohol as a predictor of drinking behavior, alcohol-related problems, and family history of alcoholism in African Americans. The convergent validity of self-reported response to alcohol (Self-Rating of the Effects of Alcohol scale [SRE]) in an African-American sample was also examined. METHOD: One hundred and three African-American young adults participated in an alcohol-challenge study, receiving a moderate dose of alcohol (0.72 g/kg alcohol for men, 0.65 g/kg for women). Breath alcohol concentration and subjective response to alcohol were assessed before beverage consumption, in 15-minute intervals for the first hour following consumption, and in 30-minute intervals thereafter. RESULTS: Latent variable growth models indicated that experiencing increased acute stimulation from alcohol was related to past-month drinking behavior and alcohol-related problems. Regression analyses indicated that the SRE was related to drinking behavior, alcohol-related problems, having an alcohol-use disorder, and a family history of alcoholism. The SRE was not related to either sedation or stimulation following alcohol administration. CONCLUSIONS: Results support alcohol response as a marker of risk for increased drinking behavior and alcohol-related problems in African Americans. Further research is required to directly compare African-American and white response to alcohol within an alcohol-challenge paradigm.
OBJECTIVE:Alcohol response is a widely studied risk factor for heavy drinking behavior and alcohol-use disorders. This study examined acute subjective response to alcohol as a predictor of drinking behavior, alcohol-related problems, and family history of alcoholism in African Americans. The convergent validity of self-reported response to alcohol (Self-Rating of the Effects of Alcohol scale [SRE]) in an African-American sample was also examined. METHOD: One hundred and three African-American young adults participated in an alcohol-challenge study, receiving a moderate dose of alcohol (0.72 g/kg alcohol for men, 0.65 g/kg for women). Breath alcohol concentration and subjective response to alcohol were assessed before beverage consumption, in 15-minute intervals for the first hour following consumption, and in 30-minute intervals thereafter. RESULTS: Latent variable growth models indicated that experiencing increased acute stimulation from alcohol was related to past-month drinking behavior and alcohol-related problems. Regression analyses indicated that the SRE was related to drinking behavior, alcohol-related problems, having an alcohol-use disorder, and a family history of alcoholism. The SRE was not related to either sedation or stimulation following alcohol administration. CONCLUSIONS: Results support alcohol response as a marker of risk for increased drinking behavior and alcohol-related problems in African Americans. Further research is required to directly compare African-American and white response to alcohol within an alcohol-challenge paradigm.
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