Literature DB >> 19259605

A novel H2O2-triggered anti-Fenton fluorescent pro-chelator excitable with visible light.

Yibin Wei1, Maolin Guo.   

Abstract

A chelator and a pro-chelator that can be activated by H(2)O(2) and subsequently sequesters iron and attenuates the Fenton reaction have been developed; both molecules are fluorescent excitable by visible light, and H(2)O(2)-activation, as well as iron-chelation, induces remarkable changes in fluorescence.

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Year:  2009        PMID： 19259605      PMCID： PMC2701733          DOI： 10.1039/b819204a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  Hydrogen peroxide triggered prochelator activation, subsequent metal chelation, and attenuation of the fenton reaction.

Authors:  Yibin Wei; Maolin Guo
Journal:  Angew Chem Int Ed Engl       Date:  2007       Impact factor: 15.336

Review 2.  Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease.

Authors:  Brian J Tabner; Stuart Turnbull; Omar M A El-Agnaf; David Allsop
Journal:  Free Radic Biol Med       Date:  2002-06-01       Impact factor: 7.376

3.  UV-visible spectroscopic study of the salicyladehyde benzoylhydrazone and its cobalt complexes.

Authors:  Yi-Heng Lu; Yu-Wei Lu; Cheng-Li Wu; Qun Shao; Xiao-Ling Chen; Rosa Ngo Biboum Bimbong
Journal:  Spectrochim Acta A Mol Biomol Spectrosc       Date:  2006-02-28       Impact factor: 4.098

4.  A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation.

Authors:  Louise K Charkoudian; David M Pham; Katherine J Franz
Journal:  J Am Chem Soc       Date:  2006-09-27       Impact factor: 15.419

Review 5.  Iron chelators for the treatment of iron overload disease: relationship between structure, redox activity, and toxicity.

Authors:  Timothy B Chaston; Des R Richardson
Journal:  Am J Hematol       Date:  2003-07       Impact factor: 10.047

6.  Iron Chelators as Potential Therapeutic Agents for Parkinson's Disease.

Authors:  Carlos A Perez; Yong Tong; Maolin Guo
Journal:  Curr Bioact Compd       Date:  2008-10-01

7.  Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders.

Authors:  Kurt Krapfenbauer; Ephrem Engidawork; Nigel Cairns; Michael Fountoulakis; Gert Lubec
Journal:  Brain Res       Date:  2003-03-28       Impact factor: 3.252

Review 8.  Neurodegenerative diseases and oxidative stress.

Authors:  Kevin J Barnham; Colin L Masters; Ashley I Bush
Journal:  Nat Rev Drug Discov       Date:  2004-03       Impact factor: 84.694

9.  Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties.

Authors:  Joan L Buss; Jiri Neuzil; Nina Gellert; Christian Weber; Prem Ponka
Journal:  Biochem Pharmacol       Date:  2003-01-15       Impact factor: 5.858
  9 in total
  4 in total

1.  A Cell-Permeable Fluorescent Prochelator Responds to Hydrogen Peroxide and Metal Ions by Decreasing Fluorescence.

Authors:  Lynne M Hyman; Katherine J Franz
Journal:  Inorganica Chim Acta       Date:  2012-01-15       Impact factor: 2.545

2.  A novel profluorescent probe for detecting oxidative stress induced by metal and H(2)O(2) in living cells.

Authors:  Yibin Wei; Yi Zhang; Zhiwei Liu; Maolin Guo
Journal:  Chem Commun (Camb)       Date:  2010-04-16       Impact factor: 6.222

3.  Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress.

Authors:  Lynne M Hyman; Clifton J Stephenson; Marina G Dickens; Ken D Shimizu; Katherine J Franz
Journal:  Dalton Trans       Date:  2009-10-16       Impact factor: 4.390

4.  Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols.

Authors:  Lynne M Hyman; Katherine J Franz
Journal:  Coord Chem Rev       Date:  2012-10-01       Impact factor: 22.315
  4 in total

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