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Literature DB >> 20396829

A novel profluorescent probe for detecting oxidative stress induced by metal and H(2)O(2) in living cells.

Yibin Wei¹, Yi Zhang, Zhiwei Liu, Maolin Guo.

Abstract

A profluorescent probe that has no fluorescent response to H(2)O(2), iron or copper ions but can be readily activated in the presence of both H(2)O(2) and Fe (or Cu) ion has been developed; the probe is capable of detecting oxidative stress promoted by Fe (or Cu) and H(2)O(2) (i.e. the Fenton reaction conditions) in living cells.

Entities: CellLine Chemical Disease Species

Mesh：

Substances：

Year: 2010 PMID： 20396829 PMCID： PMC2907239 DOI： 10.1039/c000254b

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

14 in total

1. Hydrogen peroxide triggered prochelator activation, subsequent metal chelation, and attenuation of the fenton reaction.

Authors: Yibin Wei; Maolin Guo
Journal: Angew Chem Int Ed Engl Date: 2007 Impact factor: 15.336

Review 2. Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease.

Authors: Brian J Tabner; Stuart Turnbull; Omar M A El-Agnaf; David Allsop
Journal: Free Radic Biol Med Date: 2002-06-01 Impact factor: 7.376

3. New fluorescent rhodamine hydrazone chemosensor for Cu(II) with high selectivity and sensitivity.

Authors: Yu Xiang; Aijun Tong; Peiyuan Jin; Yong Ju
Journal: Org Lett Date: 2006-06-22 Impact factor: 6.005

4. A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation.

Authors: Louise K Charkoudian; David M Pham; Katherine J Franz
Journal: J Am Chem Soc Date: 2006-09-27 Impact factor: 15.419

5. A copper(II)-selective chelator ameliorates left-ventricular hypertrophy in type 2 diabetic patients: a randomised placebo-controlled study.

Authors: G J S Cooper; A A Young; G D Gamble; C J Occleshaw; A M Dissanayake; B R Cowan; D H Brunton; J R Baker; A R J Phillips; C M Frampton; S D Poppitt; R N Doughty
Journal: Diabetologia Date: 2009-01-27 Impact factor: 10.122

Review 6. Mechanisms for copper acquisition, distribution and regulation.

Authors: Byung-Eun Kim; Tracy Nevitt; Dennis J Thiele
Journal: Nat Chem Biol Date: 2008-03 Impact factor: 15.040

Review 7. Iron chelators for the treatment of iron overload disease: relationship between structure, redox activity, and toxicity.

Authors: Timothy B Chaston; Des R Richardson
Journal: Am J Hematol Date: 2003-07 Impact factor: 10.047

8. Iron Chelators as Potential Therapeutic Agents for Parkinson's Disease.

Authors: Carlos A Perez; Yong Tong; Maolin Guo
Journal: Curr Bioact Compd Date: 2008-10-01

9. Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders.

Authors: Kurt Krapfenbauer; Ephrem Engidawork; Nigel Cairns; Michael Fountoulakis; Gert Lubec
Journal: Brain Res Date: 2003-03-28 Impact factor: 3.252

Review 10. Neurodegenerative diseases and oxidative stress.

Authors: Kevin J Barnham; Colin L Masters; Ashley I Bush
Journal: Nat Rev Drug Discov Date: 2004-03 Impact factor: 84.694

5 in total

1. A Cell-Permeable Fluorescent Prochelator Responds to Hydrogen Peroxide and Metal Ions by Decreasing Fluorescence.

Authors: Lynne M Hyman; Katherine J Franz
Journal: Inorganica Chim Acta Date: 2012-01-15 Impact factor: 2.545

2. A novel near-infrared turn-on and ratiometric fluorescent probe capable of copper(ii) ion determination in living cells.

Authors: Ziya Aydin; Bing Yan; Yibin Wei; Maolin Guo
Journal: Chem Commun (Camb) Date: 2020-05-19 Impact factor: 6.222

A novel profluorescent probe for detecting oxidative stress induced by metal and H(2)O(2) in living cells.

1. Hydrogen peroxide triggered prochelator activation, subsequent metal chelation, and attenuation of the fenton reaction.

Review 2. Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease.

3. New fluorescent rhodamine hydrazone chemosensor for Cu(II) with high selectivity and sensitivity.

4. A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation.

5. A copper(II)-selective chelator ameliorates left-ventricular hypertrophy in type 2 diabetic patients: a randomised placebo-controlled study.

Review 6. Mechanisms for copper acquisition, distribution and regulation.

Review 7. Iron chelators for the treatment of iron overload disease: relationship between structure, redox activity, and toxicity.

8. Iron Chelators as Potential Therapeutic Agents for Parkinson's Disease.

9. Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders.

Review 10. Neurodegenerative diseases and oxidative stress.

1. A Cell-Permeable Fluorescent Prochelator Responds to Hydrogen Peroxide and Metal Ions by Decreasing Fluorescence.

2. A novel near-infrared turn-on and ratiometric fluorescent probe capable of copper(ii) ion determination in living cells.

3. Facile synthesis of a novel genetically encodable fluorescent α-amino acid emitting greenish blue light.

4. Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols.

Review 5. Progress of Advanced Nanomaterials in the Non-Enzymatic Electrochemical Sensing of Glucose and H₂O₂.

Review 2. Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease.

Review 6. Mechanisms for copper acquisition, distribution and regulation.

Review 7. Iron chelators for the treatment of iron overload disease: relationship between structure, redox activity, and toxicity.

Review 10. Neurodegenerative diseases and oxidative stress.

Review 5. Progress of Advanced Nanomaterials in the Non-Enzymatic Electrochemical Sensing of Glucose and H2O2.

Review 5. Progress of Advanced Nanomaterials in the Non-Enzymatic Electrochemical Sensing of Glucose and H₂O₂.