Literature DB >> 19259122

Visualizing the twists and turns of a molecular chaperone.

Len Neckers, Shinji Tsutsumi, Mehdi Mollapour.   

Abstract

Mesh：

Substances：

Year:  2009        PMID： 19259122     DOI： 10.1038/nsmb0309-235

Source DB:  PubMed          Journal:  Nat Struct Mol Biol        ISSN： 1545-9985            Impact factor:   15.369


× No keyword cloud information.
  19 in total

1.  Structure of an Hsp90-Cdc37-Cdk4 complex.

Authors:  Cara K Vaughan; Ulrich Gohlke; Frank Sobott; Valerie M Good; Maruf M U Ali; Chrisostomos Prodromou; Carol V Robinson; Helen R Saibil; Laurence H Pearl
Journal:  Mol Cell       Date:  2006-09-01       Impact factor: 17.970

Review 2.  Structure and mechanism of the Hsp90 molecular chaperone machinery.

Authors:  Laurence H Pearl; Chrisostomos Prodromou
Journal:  Annu Rev Biochem       Date:  2006       Impact factor: 23.643

Review 3.  Tumor selectivity of Hsp90 inhibitors: the explanation remains elusive.

Authors:  Gabriela Chiosis; Len Neckers
Journal:  ACS Chem Biol       Date:  2006-06-20       Impact factor: 5.100

Review 4.  The Hsp90 chaperone machinery.

Authors:  Sebastian Karl Wandinger; Klaus Richter; Johannes Buchner
Journal:  J Biol Chem       Date:  2008-04-28       Impact factor: 5.157

5.  Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements.

Authors:  Andrew K Shiau; Seth F Harris; Daniel R Southworth; David A Agard
Journal:  Cell       Date:  2006-10-20       Impact factor: 41.582

6.  Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions.

Authors:  Philippe Meyer; Chrisostomos Prodromou; Bin Hu; Cara Vaughan; S Mark Roe; Barry Panaretou; Peter W Piper; Laurence H Pearl
Journal:  Mol Cell       Date:  2003-03       Impact factor: 17.970

Review 7.  Hsp90 inhibitors as novel cancer chemotherapeutic agents.

Authors:  Len Neckers
Journal:  Trends Mol Med       Date:  2002       Impact factor: 11.951

8.  The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains.

Authors:  C Prodromou; B Panaretou; S Chohan; G Siligardi; R O'Brien; J E Ladbury; S M Roe; P W Piper; L H Pearl
Journal:  EMBO J       Date:  2000-08-15       Impact factor: 11.598

9.  The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis.

Authors:  Moritz Mickler; Martin Hessling; Christoph Ratzke; Johannes Buchner; Thorsten Hugel
Journal:  Nat Struct Mol Biol       Date:  2009-02-22       Impact factor: 15.369

10.  A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors.

Authors:  Adeela Kamal; Lia Thao; John Sensintaffar; Lin Zhang; Marcus F Boehm; Lawrence C Fritz; Francis J Burrows
Journal:  Nature       Date:  2003-09-25       Impact factor: 49.962
View more
  9 in total

1.  Hsp90 cochaperone Aha1 is a negative regulator of the Saccharomyces MAL activator and acts early in the chaperone activation pathway.

Authors:  Fulai Ran; Nidhi Gadura; Corinne A Michels
Journal:  J Biol Chem       Date:  2010-02-22       Impact factor: 5.157

2.  Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis.

Authors:  Atanas V Koulov; Paul LaPointe; Bingwen Lu; Abbas Razvi; Judith Coppinger; Meng-Qiu Dong; Jeanne Matteson; Rob Laister; Cheryl Arrowsmith; John R Yates; William E Balch
Journal:  Mol Biol Cell       Date:  2010-01-20       Impact factor: 4.138

Review 3.  Hsp90 and co-chaperones twist the functions of diverse client proteins.

Authors:  Abbey Zuehlke; Jill L Johnson
Journal:  Biopolymers       Date:  2010-03       Impact factor: 2.505

Review 4.  Alternate strategies of Hsp90 modulation for the treatment of cancer and other diseases.

Authors:  Gary E L Brandt; Brian S J Blagg
Journal:  Curr Top Med Chem       Date:  2009       Impact factor: 3.295

5.  A detailed modular analysis of heat-shock protein dynamics under acute and chronic stress and its implication in anxiety disorders.

Authors:  K Sriram; Maria Rodriguez-Fernandez; Francis J Doyle
Journal:  PLoS One       Date:  2012-08-22       Impact factor: 3.240

6.  In Silico Studies on Fungal Metabolite against Skin Cancer Protein (4,5-Diarylisoxazole HSP90 Chaperone).

Authors:  Saravanakumar Kandasamy; Sunil Kumar Sahu; Kathiresan Kandasamy
Journal:  ISRN Dermatol       Date:  2012-09-06

7.  Corresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulations.

Authors:  Giulia Morra; Raffaello Potestio; Cristian Micheletti; Giorgio Colombo
Journal:  PLoS Comput Biol       Date:  2012-03-22       Impact factor: 4.475

8.  Thermodynamics of aryl-dihydroxyphenyl-thiadiazole binding to human Hsp90.

Authors:  Egidijus Kazlauskas; Vilma Petrikaitė; Vilma Michailovienė; Jurgita Revuckienė; Jurgita Matulienė; Leonas Grinius; Daumantas Matulis
Journal:  PLoS One       Date:  2012-05-24       Impact factor: 3.240

9.  Targeting heat shock protein 90 for the treatment of malignant pheochromocytoma.

Authors:  Alessio Giubellino; Carole Sourbier; Min-Jung Lee; Brad Scroggins; Petra Bullova; Michael Landau; Weiwen Ying; Len Neckers; Jane B Trepel; Karel Pacak
Journal:  PLoS One       Date:  2013-02-14       Impact factor: 3.240
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.