OBJECTIVE: Identification and estimation, by clinical pharmacists participating in routine medical rounds, of drug-related problems (DRPs), arising despite the use of a computerized physician order entry (CPOE) system. METHODS: An 18-month prospective study of DRPs through a CPOE was conducted by seven clinical pharmacists participating in ward activity. DRPs were identified by two independent pharmacists using a structured order review (French Society of Clinical Pharmacy instrument). RESULTS: A total of 29 016 medication orders relating to 8152 patients were analysed, and 2669 DRPs, involving 1564 patients (56% female; mean age 72.6 years), were identified representing 33 DRPs per 100 admissions. The most commonly identified DRPs were non-conformity to guidelines or contra-indication (29.5%), improper administration (19.6%), drug interaction (16.7%) and overdosage (12.8%). There were 429 different drugs associated with these DRPs. Cardiovascular drugs were the most frequently implicated (22.2%), followed by antibiotics/anti-infectives (13.3%) and analgesics/antiinflammatory drugs (11.3%). Different types of DRPs were closely associated with specific classes of drugs. CONCLUSIONS: Drug-related problems are common even after implementation of CPOE. In this context, routine participation of clinical pharmacists in clinical medical rounds may facilitate identification of DRPs. Pharmacists should be able to enhance patient safety through such involvement.
OBJECTIVE: Identification and estimation, by clinical pharmacists participating in routine medical rounds, of drug-related problems (DRPs), arising despite the use of a computerized physician order entry (CPOE) system. METHODS: An 18-month prospective study of DRPs through a CPOE was conducted by seven clinical pharmacists participating in ward activity. DRPs were identified by two independent pharmacists using a structured order review (French Society of Clinical Pharmacy instrument). RESULTS: A total of 29 016 medication orders relating to 8152 patients were analysed, and 2669 DRPs, involving 1564 patients (56% female; mean age 72.6 years), were identified representing 33 DRPs per 100 admissions. The most commonly identified DRPs were non-conformity to guidelines or contra-indication (29.5%), improper administration (19.6%), drug interaction (16.7%) and overdosage (12.8%). There were 429 different drugs associated with these DRPs. Cardiovascular drugs were the most frequently implicated (22.2%), followed by antibiotics/anti-infectives (13.3%) and analgesics/antiinflammatory drugs (11.3%). Different types of DRPs were closely associated with specific classes of drugs. CONCLUSIONS: Drug-related problems are common even after implementation of CPOE. In this context, routine participation of clinical pharmacists in clinical medical rounds may facilitate identification of DRPs. Pharmacists should be able to enhance patient safety through such involvement.
Authors: Rianne J Zaal; Mark M P M Jansen; Marjolijn Duisenberg-van Essenberg; Cees C Tijssen; Jan A Roukema; Patricia M L A van den Bemt Journal: Int J Clin Pharm Date: 2013-05-29
Authors: Salah M Aburuz; Nailya R Bulatova; Al-Moatasem M Yousef; Mutasim A Al-Ghazawi; Izzat A Alawwa; Akram Al-Saleh Journal: Int J Clin Pharm Date: 2011-03-26
Authors: Thilo Bertsche; Johannes Pfaff; Petra Schiller; Jens Kaltschmidt; Markus G Pruszydlo; Wolfgang Stremmel; Ingeborg Walter-Sack; Walter E Haefeli; Jens Encke Journal: Intensive Care Med Date: 2010-02-09 Impact factor: 17.440
Authors: Tosha B Wetterneck; James M Walker; Mary Ann Blosky; Randi S Cartmill; Peter Hoonakker; Mark A Johnson; Evan Norfolk; Pascale Carayon Journal: J Am Med Inform Assoc Date: 2011-07-29 Impact factor: 4.497