| Literature DB >> 19245240 |
Juan He1, Xuan-Qin Chen, Ming-Ming Li, Yu Zhao, Gang Xu, Xiao Cheng, Li-Yan Peng, Min-Jin Xie, Yong-Tang Zheng, Yi-Ping Wang, Qin-Shi Zhao.
Abstract
Lycojapodine A, a novel C(16)N-type Lycopodium alkaloid with an unprecedented 6/6/6/7 tetracyclic ring system, was isolated from the club moss Lycopodium japonicum. The structure and relative stereochemistry were elucidated on the basis of spectroscopic data and were further confirmed by X-ray analysis. A possible biosynthetic pathway for 1 was proposed. Its inhibitory activity on acetylcholinestrease and anti-HIV-1 activity were also evaluated.Entities:
Mesh：
Substances：
Year: 2009 PMID： 19245240 DOI： 10.1021/ol900079t
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005