Literature DB >> 19239261

A new and facile synthesis of quinazoline-2,4(1H,3H)-diones.

Jiarong Li1, Xian Chen, Daxin Shi, Shuling Ma, Qing Li, Qi Zhang, Jianhong Tang.   

Abstract

A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl(2) (0.5-10 mol %) at 190-200 degrees C in the sealed reactor.

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Year:  2009        PMID: 19239261     DOI: 10.1021/ol900093h

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  8 in total

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Authors:  Tejas M Dhameliya; Hiren A Donga; Punit V Vaghela; Bhoomi G Panchal; Dipen K Sureja; Kunjan B Bodiwala; Mahesh T Chhabria
Journal:  RSC Adv       Date:  2020-09-03       Impact factor: 4.036

2.  A new and facile synthetic approach to substituted 2-thioxoquinazolin-4-ones by the annulation of a pyrimidine derivative.

Authors:  Nimalini Devi Moirangthem; Warjeet Singh Laitonjam
Journal:  Beilstein J Org Chem       Date:  2010-11-09       Impact factor: 2.883

3.  Spiro-[cyclo-pentane-1,2'(1'H)-pyrido[2,3-d]pyrimidin]-4'(3'H)-one.

Authors:  Daxin Shi; Liupan Yang; Jianhong Tang; Xiuzhen Wang; Jiarong Li
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-08-18

4.  2,4-Dichloro-7-fluoro-quinazoline.

Authors:  Feng Gao; Yun-Fei Hu; Jin-Long Wang
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-02-17

5.  DMAP-Catalyzed One-Pot Synthesis of Quinazoline-2,4-diones from 2-Aminobenzamides and Di-tert-butyl Dicarbonate.

Authors:  Hui Chen; Peng Li; Rongfei Qin; Hong Yan; Gang Li; Haihong Huang
Journal:  ACS Omega       Date:  2020-04-16

6.  Basic ionic liquid as catalyst and surfactant: green synthesis of quinazolinone in aqueous media.

Authors:  Yaping Zhang; Bin Zhen; Hansheng Li; Yaqing Feng
Journal:  RSC Adv       Date:  2018-10-31       Impact factor: 3.361

7.  ZnCl2-promoted domino reaction of 2-hydroxybenzonitriles with ketones for synthesis of 1,3-benzoxazin-4-ones.

Authors:  Ziqi Su; Hongxin Chai; Juan Xu; Jiarong Li
Journal:  RSC Adv       Date:  2021-09-06       Impact factor: 4.036

8.  Design, Synthesis and Bioactivity Evaluation of Coumarin-BMT Hybrids as New Acetylcholinesterase Inhibitors.

Authors:  Fanxin Zeng; Tao Lu; Jie Wang; Xuliang Nie; Wanming Xiong; Zhongping Yin; Dayong Peng
Journal:  Molecules       Date:  2022-03-26       Impact factor: 4.411

  8 in total

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