Literature DB >> 19226154

Antineoplastic agents. 570. Isolation and structure elucidation of bacillistatins 1 and 2 from a marine Bacillus silvestris.

George R Pettit1, John C Knight, Delbert L Herald, Robin K Pettit, Fiona Hogan, Venugopal J R V Mukku, John S Hamblin, Michael J Dodson, Jean-Charles Chapuis.   

Abstract

Two new cyclodepsipeptides designated bacillistatins 1 (1) and 2 (2) have been isolated from cultures of a sample of Bacillus silvestris that was obtained from a Pacific Ocean (southern Chile) crab. Each 12-unit cyclodepsipeptide strongly inhibited growth of a human cancer cell line panel, with GI(50)'s of 10(-4)-10(-5) microg/mL, and each compound was active against antibiotic-resistant Streptococcus pneumoniae. The structures were elucidated by a combination of X-ray diffraction and mass and 2D NMR spectroscopic analyses, together with chemical degradation.

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Year:  2009        PMID： 19226154      PMCID： PMC2765486          DOI： 10.1021/np800603u

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  28 in total

1.  Venturamides A and B: antimalarial constituents of the panamanian marine Cyanobacterium Oscillatoria sp.

Authors:  Roger G Linington; José Gonzalez; Luis-David Ureña; Luz I Romero; Eduardo Ortega-Barría; William H Gerwick
Journal:  J Nat Prod       Date:  2007-03-01       Impact factor: 4.050

Review 2.  Bioactive macrolides and polyketides from marine dinoflagellates of the genus Amphidinium.

Authors:  Jun'ichi Kobayashi; Takaaki Kubota
Journal:  J Nat Prod       Date:  2007-03-03       Impact factor: 4.050

3.  Pentaketides relating to aspinonene and dihydroaspyrone from a marine-derived fungus, Aspergillus ostianus.

Authors:  Keijiro Kito; Ryuhei Ookura; Sanae Yoshida; Michio Namikoshi; Takashi Ooi; Takenori Kusumi
Journal:  J Nat Prod       Date:  2007-11-10       Impact factor: 4.050

4.  Citromycetins and bilains A-C: new aromatic polyketides and diketopiperazines from Australian marine-derived and terrestrial Penicillium spp.

Authors:  Robert J Capon; Michael Stewart; Ranjala Ratnayake; Ernest Lacey; Jennifer H Gill
Journal:  J Nat Prod       Date:  2007-10-25       Impact factor: 4.050

5.  Amphidinolides B6 and B7, cytotoxic macrolides from a symbiotic dinoflagellate Amphidinium species.

Authors:  Keiko Oguchi; Masashi Tsuda; Rie Iwamoto; Yumiko Okamoto; Taeko Endo; Jun'ichi Kobayashi; Tomoko Ozawa; Atsunori Masuda
Journal:  J Nat Prod       Date:  2007-10-09       Impact factor: 4.050

6.  Iriomoteolides-1b and -1c, 20-membered macrolides from a marine dinoflagellate Amphidinium species.

Authors:  Masashi Tsuda; Keiko Oguchi; Rie Iwamoto; Yumiko Okamoto; Eri Fukushi; Jun Kawabata; Tomoko Ozawa; Atsunori Masuda
Journal:  J Nat Prod       Date:  2007-10-11       Impact factor: 4.050

7.  Lyngbyastatins 5-7, potent elastase inhibitors from Floridian marine cyanobacteria, Lyngbya spp.

Authors:  Kanchan Taori; Susan Matthew; James R Rocca; Valerie J Paul; Hendrik Luesch
Journal:  J Nat Prod       Date:  2007-10-03       Impact factor: 4.050

8.  The berkeleyacetals, three meroterpenes from a deep water acid mine waste Penicillium.

Authors:  Donald B Stierle; Andrea A Stierle; Brianna Patacini
Journal:  J Nat Prod       Date:  2007-10-31       Impact factor: 4.050

9.  Marmycins A and B, cytotoxic pentacyclic C-glycosides from a marine sediment-derived actinomycete related to the genus Streptomyces.

Authors:  Glenroy D A Martin; Lik T Tan; Paul R Jensen; Rosalba Encarnacion Dimayuga; Craig R Fairchild; Carmen Raventos-Suarez; William Fenical
Journal:  J Nat Prod       Date:  2007-09-11       Impact factor: 4.050

10.  Cyclic depsipeptides, ichthyopeptins A and B, from Microcystis ichthyoblabe.

Authors:  Elmi N Zainuddin; Renate Mentel; Victor Wray; Rolf Jansen; Manfred Nimtz; Michael Lalk; Sabine Mundt
Journal:  J Nat Prod       Date:  2007-06-28       Impact factor: 4.050
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  15 in total

1.  Psychrotolerant Paenibacillus tundrae isolates from barley grains produce new cereulide-like depsipeptides (paenilide and homopaenilide) that are highly toxic to mammalian cells.

Authors:  Stiina Rasimus; Raimo Mikkola; Maria A Andersson; Vera V Teplova; Natalia Venediktova; Christine Ek-Kommonen; Mirja Salkinoja-Salonen
Journal:  Appl Environ Microbiol       Date:  2012-03-09       Impact factor: 4.792

2.  Antineoplastic agents. 571. Total synthesis of bacillistatin 2.

Authors:  George R Pettit; Shougang Hu; John C Knight; Jean-Charles Chapuis
Journal:  J Nat Prod       Date:  2009-03-27       Impact factor: 4.050

3.  Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide.

Authors:  Amber M King; Marc De Ryck; Rafal Kaminski; Anne Valade; James P Stables; Harold Kohn
Journal:  J Med Chem       Date:  2011-09-13       Impact factor: 7.446

4.  Antineoplastic agents. 590. X-ray crystal structure of dolastatin 16 and syntheses of the dolamethylleuine and dolaphenvaline units.

Authors:  George R Pettit; Thomas H Smith; Jun-Ping Xu; Delbert L Herald; Erik J Flahive; Collin R Anderson; Paul E Belcher; John C Knight
Journal:  J Nat Prod       Date:  2011-05-03       Impact factor: 4.050

Review 5.  Marine Cyclic Peptides: Antimicrobial Activity and Synthetic Strategies.

Authors:  Ricardo Ribeiro; Eugénia Pinto; Carla Fernandes; Emília Sousa
Journal:  Mar Drugs       Date:  2022-06-15       Impact factor: 6.085

6.  Gut Bacteria of Columbia livia Are a Potential Source of Anti-Tumour Molecules.

Authors:  Morhanavallee Soopramanien; Naveed Khan; Bibi Noorheen Haleema Mooneerah Neerooa; Kuppusamy Sagathevan; Ruqaiyyah Siddiqui
Journal:  Asian Pac J Cancer Prev       Date:  2021-03-01

7.  The second skin: ecological role of epibiotic biofilms on marine organisms.

Authors:  Martin Wahl; Franz Goecke; Antje Labes; Sergey Dobretsov; Florian Weinberger
Journal:  Front Microbiol       Date:  2012-08-23       Impact factor: 5.640

Review 8.  Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates.

Authors:  Marla Trindade; Leonardo Joaquim van Zyl; José Navarro-Fernández; Ahmed Abd Elrazak
Journal:  Front Microbiol       Date:  2015-08-28       Impact factor: 5.640

Review 9.  Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2013-07-16       Impact factor: 5.118

Review 10.  Diversity of secondary metabolites from marine Bacillus species: chemistry and biological activity.

Authors:  Muhammad Abdul Mojid Mondol; Hee Jae Shin; Mohammad Tofazzal Islam
Journal:  Mar Drugs       Date:  2013-08-12       Impact factor: 5.118
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