Literature DB >> 19224215

[Gene expression analyses of kidney biopsies: the European renal cDNA bank--Kröner-Fresenius biopsy bank].

C D Cohen1, M Kretzler.   

Abstract

Histological analysis of kidney biopsies is an essential part of our current diagnostic workup of patients with renal disease. Besides the already established diagnostic tools, new methods allow extensive analysis of the sample tissue's gene expression. Using results from a European multicenter study on gene expression analysis of renal biopsies, in this review we demonstrate that this novel approach not only expands the scope of so-called basic research but also might supplement future biopsy diagnostics. The goals are improved diagnosis and more specific therapy choice and prognosis estimates.

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Year:  2009        PMID: 19224215     DOI: 10.1007/s00292-008-1111-2

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  17 in total

1.  Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease.

Authors:  Sanja Sever; Mehmet M Altintas; Sharif R Nankoe; Clemens C Möller; David Ko; Changli Wei; Joel Henderson; Elizabetta C del Re; Lianne Hsing; Ann Erickson; Clemens D Cohen; Matthias Kretzler; Dontscho Kerjaschki; Alexander Rudensky; Boris Nikolic; Jochen Reiser
Journal:  J Clin Invest       Date:  2007-08       Impact factor: 14.808

2.  A novel method for real time quantitative RT-PCR.

Authors:  U E Gibson; C A Heid; P M Williams
Journal:  Genome Res       Date:  1996-10       Impact factor: 9.043

3.  Methotrexate prevents renal injury in experimental diabetic rats via anti-inflammatory actions.

Authors:  Kosuke Yozai; Kenichi Shikata; Motofumi Sasaki; Atsuhiro Tone; Sakiko Ohga; Hitomi Usui; Shinichi Okada; Jun Wada; Ryo Nagase; Daisuke Ogawa; Yasushi Shikata; Hirofumi Makino
Journal:  J Am Soc Nephrol       Date:  2005-09-21       Impact factor: 10.121

4.  PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases.

Authors:  Frank Eitner; Tammo Ostendorf; Matthias Kretzler; Clemens D Cohen; Ulf Eriksson; Hermann-Josef Gröne; Jürgen Floege
Journal:  J Am Soc Nephrol       Date:  2003-05       Impact factor: 10.121

5.  Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice.

Authors:  Mei Ding; Shiying Cui; Chengjin Li; Serge Jothy; Volker Haase; Brent M Steer; Philip A Marsden; Jeffrey Pippin; Stuart Shankland; Maria Pia Rastaldi; Clemens D Cohen; Matthias Kretzler; Susan E Quaggin
Journal:  Nat Med       Date:  2006-08-13       Impact factor: 53.440

6.  Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss.

Authors:  H J Baelde; M Eikmans; D W P Lappin; P P Doran; D Hohenadel; P-T Brinkkoetter; F J van der Woude; R Waldherr; T J Rabelink; E de Heer; J A Bruijn
Journal:  Kidney Int       Date:  2007-01-31       Impact factor: 10.612

7.  Potential role of fractalkine receptor expression in human renal fibrogenesis.

Authors:  M J Koziolek; H Schmid; C D Cohen; S Blaschke; B Hemmerlein; A Zapf; G A Müller; F Strutz
Journal:  Kidney Int       Date:  2007-06-20       Impact factor: 10.612

8.  Interstitial vascular rarefaction and reduced VEGF-A expression in human diabetic nephropathy.

Authors:  Maja T Lindenmeyer; Matthias Kretzler; Anissa Boucherot; Silvia Berra; Yoshinari Yasuda; Anna Henger; Felix Eichinger; Stefanie Gaiser; Holger Schmid; Maria P Rastaldi; Robert W Schrier; Detlef Schlöndorff; Clemens D Cohen
Journal:  J Am Soc Nephrol       Date:  2007-05-02       Impact factor: 10.121

9.  Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition.

Authors:  Debra F Higgins; Kuniko Kimura; Wanja M Bernhardt; Nikita Shrimanker; Yasuhiro Akai; Bernd Hohenstein; Yoshihiko Saito; Randall S Johnson; Matthias Kretzler; Clemens D Cohen; Kai-Uwe Eckardt; Masayuki Iwano; Volker H Haase
Journal:  J Clin Invest       Date:  2007-12       Impact factor: 14.808

10.  Gene expression fingerprints in human tubulointerstitial inflammation and fibrosis as prognostic markers of disease progression.

Authors:  Anna Henger; Matthias Kretzler; Peter Doran; Mahnaz Bonrouhi; Holger Schmid; Eva Kiss; Clemens D Cohen; Stephen Madden; Stefan Porubsky; Elisabeth F Gröne; Detlef Schlöndorff; Peter J Nelson; Hermann-Josef Gröne
Journal:  Kidney Int       Date:  2004-03       Impact factor: 10.612

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  2 in total

Review 1.  Cellular and molecular interrogation of kidney biopsy specimens.

Authors:  Michael T Eadon; Pierre C Dagher; Tarek M El-Achkar
Journal:  Curr Opin Nephrol Hypertens       Date:  2022-03-01       Impact factor: 2.894

Review 2.  Techniques and Approaches to Genetic Analyses in Nephrological Disorders.

Authors:  Laurel K Willig
Journal:  J Pediatr Genet       Date:  2015-08-13
  2 in total

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