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Literature DB >> 19222065

A reduced SNARE model for membrane fusion.

Hana Robson Marsden¹, Nina A Elbers, Paul H H Bomans, Nico A J M Sommerdijk, Alexander Kros.

Abstract

Let's get together: A minimal model system was developed to mimic the SNARE-protein-mediated fusion of biological membranes (see picture). Fusion between two populations of liposomes is controlled by a pair of complementary lipidated oligopeptides that form noncovalent coiled-coil complexes and thereby force the membranes into close proximity to promote fusion. The model system displays the key characteristics of in vivo fusion events.

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Year: 2009 PMID： 19222065 DOI： 10.1002/anie.200804493

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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Cited

31 in total

1. Synthetic beta cells for fusion-mediated dynamic insulin secretion.

Authors: Zhaowei Chen; Jinqiang Wang; Wujin Sun; Edikan Archibong; Anna R Kahkoska; Xudong Zhang; Yue Lu; Frances S Ligler; John B Buse; Zhen Gu
Journal: Nat Chem Biol Date: 2017-10-30 Impact factor: 15.040

2. Highly Efficient Protein-free Membrane Fusion: A Giant Vesicle Study.

Authors: Rafael B Lira; Tom Robinson; Rumiana Dimova; Karin A Riske
Journal: Biophys J Date: 2018-12-01 Impact factor: 4.033

3. Preparation of size tunable giant vesicles from cross-linked dextran(ethylene glycol) hydrogels.

Authors: Néstor López Mora; Jesper S Hansen; Yue Gao; Andrew A Ronald; Roxanne Kieltyka; Noah Malmstadt; Alexander Kros
Journal: Chem Commun (Camb) Date: 2014-02-25 Impact factor: 6.222

4. Interaction of SNARE Mimetic Peptides with Lipid bilayers: Effects of Secondary Structure, Bilayer Composition and Lipid Anchoring.

Authors: Swapnil Wagle; Vasil N Georgiev; Tom Robinson; Rumiana Dimova; Reinhard Lipowsky; Andrea Grafmüller
Journal: Sci Rep Date: 2019-05-22 Impact factor: 4.379

5. Geometry of the Contact Zone between Fused Membrane-Coated Beads Mimicking Cell-Cell Fusion.

Authors: Filip Savić; Torben-Tobias Kliesch; Sarah Verbeek; Chunxiao Bao; Jan Thiart; Alexander Kros; Burkhard Geil; Andreas Janshoff
Journal: Biophys J Date: 2016-05-24 Impact factor: 4.033

6. A Coiled-Coil Peptide Shaping Lipid Bilayers upon Fusion.

Authors: Martin Rabe; Christopher Aisenbrey; Kristyna Pluhackova; Vincent de Wert; Aimee L Boyle; Didjay F Bruggeman; Sonja A Kirsch; Rainer A Böckmann; Alexander Kros; Jan Raap; Burkhard Bechinger
Journal: Biophys J Date: 2016-11-15 Impact factor: 4.033

A reduced SNARE model for membrane fusion.

1. Synthetic beta cells for fusion-mediated dynamic insulin secretion.

2. Highly Efficient Protein-free Membrane Fusion: A Giant Vesicle Study.

3. Preparation of size tunable giant vesicles from cross-linked dextran(ethylene glycol) hydrogels.

4. Interaction of SNARE Mimetic Peptides with Lipid bilayers: Effects of Secondary Structure, Bilayer Composition and Lipid Anchoring.

5. Geometry of the Contact Zone between Fused Membrane-Coated Beads Mimicking Cell-Cell Fusion.

6. A Coiled-Coil Peptide Shaping Lipid Bilayers upon Fusion.

7. Design and Application of Stimulus-Responsive Droplets and Bubbles Stabilized by Phospholipid Monolayers.

Review 8. Molecular machines governing exocytosis of synaptic vesicles.

9. Coiled-coil formation on lipid bilayers--implications for docking and fusion efficiency.

10. Individual vesicle fusion events mediated by lipid-anchored DNA.