| Literature DB >> 19217769 |
António R Guerreiro1, Iva Chianella, Elena Piletska, Michael J Whitcombe, Sergey A Piletsky.
Abstract
Soluble molecularly imprinted nanoparticles were synthesised via iniferter initiated polymerisation and separated by size via gel permeation chromatography. Subsequent fractionation of these particles by affinity chromatography allowed the separation of high affinity fractions from the mixture of nanoparticles. Fractions selected this way possess affinity similar to that of natural antibodies (K(d) 6.6x10(-8)) M and were also able to discriminate between related functional analogues of the template.Mesh:
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Year: 2009 PMID: 19217769 DOI: 10.1016/j.bios.2009.01.013
Source DB: PubMed Journal: Biosens Bioelectron ISSN: 0956-5663 Impact factor: 10.618