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Literature DB >> 19212130

Sex hormones and modulation of immunity against leishmaniasis.

Heidi Snider¹, Claudio Lezama-Davila, James Alexander, Abhay R Satoskar.

Abstract

Sex-associated hormones such as estradiol, testosterone and progesterone have all been shown to modulate immune responses, which can result in differential disease outcomes between males and females, as well as between pregnant and nonpregnant females. Most parasitic diseases, including leishmaniasis, usually result in more severe disease in males compared with females. This review highlights our current knowledge concerning the role of sex hormones in modulating leishmaniasis in both clinical settings and experimental disease models. Copyright (c) 2009 S. Karger AG, Basel.

Entities: Chemical Disease Gene Species

Mesh：

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Year: 2009 PMID： 19212130 PMCID： PMC2760305 DOI： 10.1159/000180265

Source DB: PubMed Journal: Neuroimmunomodulation ISSN： 1021-7401 Impact factor: 2.492

82 in total

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