Literature DB >> 19211385

Techniques of peripheral nerve repair.

L B Dahlin1.   

Abstract

Nerve injuries extend from simple nerve compression lesions to complete nerve injuries and severe lacerations of the nerve trunks. A specific problem is brachial plexus injuries where nerve roots can be ruptured, or even avulsed from the spinal cord, by traction. An early and correct diagnosis of a nerve injury is important. A thorough knowledge of the anatomy of the peripheral nerve trunk as well as of basic neurobiological alterations in neurons and Schwann cells induced by the injury are crucial for the surgeon in making adequate decisions on how to repair and reconstruct nerves. The technique of peripheral nerve repair includes four important steps (preparation of nerve end, approximation, coaptation and maintenance). Nerves are usually repaired primarily with sutures applied in the different tissue components, but various tubes are available. Nerve grafts and nerve transfers are alternatives when the injury induces a nerve defect. Timing of nerve repair is essential. An early repair is preferable since it is advantageous for neurobiological reasons. Postoperative rehabilitation, utilising the patients' own coping strategies, with evaluation of outcome are additional important steps in treatment of peripheral nerve injuries. in the rehabilitation phase adequate handling of pain, allodynia and cold intolerance are emphasised.

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Year:  2008        PMID: 19211385     DOI: 10.1177/145749690809700407

Source DB:  PubMed          Journal:  Scand J Surg        ISSN: 1457-4969            Impact factor:   2.360


  30 in total

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Review 2.  Overcoming short gaps in peripheral nerve repair: conduits and human acellular nerve allograft.

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Journal:  Hand (N Y)       Date:  2014-06

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Journal:  Tissue Eng Part A       Date:  2015-01-08       Impact factor: 3.845

4.  Neural Differentiation of Human-Induced Pluripotent Stem Cells (hiPSc) on Surface-Modified Nanofibrous Scaffolds Coated with Platelet-Rich Plasma.

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Review 5.  Plastic fantastic: Schwann cells and repair of the peripheral nervous system.

Authors:  Haesun A Kim; Thomas Mindos; David B Parkinson
Journal:  Stem Cells Transl Med       Date:  2013-07-01       Impact factor: 6.940

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8.  Reconstruction of sciatic nerve after traumatic injury in humans - factors influencing outcome as related to neurobiological knowledge from animal research.

Authors:  Amanda Maripuu; Anders Björkman; Isabella M Björkman-Burtscher; Peter Mannfolk; Gert Andersson; Lars B Dahlin
Journal:  J Brachial Plex Peripher Nerve Inj       Date:  2012-10-10

9.  An anatomical study of porcine peripheral nerve and its potential use in nerve tissue engineering.

Authors:  Leyla Zilic; Philippa E Garner; Tong Yu; Sabiniano Roman; John W Haycock; Stacy-Paul Wilshaw
Journal:  J Anat       Date:  2015-07-21       Impact factor: 2.610

10.  Growth factor choice is critical for successful functionalization of nanoparticles.

Authors:  Josephine Pinkernelle; Vittoria Raffa; Maria P Calatayud; Gerado F Goya; Cristina Riggio; Gerburg Keilhoff
Journal:  Front Neurosci       Date:  2015-09-02       Impact factor: 4.677

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