| Literature DB >> 19209924 |
Matthew L Crawley1, Kristin M Phipps, Igor Goljer, John F Mehlmann, Joseph T Lundquist, John W Ullrich, Cuijian Yang, Paige E Mahaney.
Abstract
An efficient and mild method to couple aryl bromides and activated non-allylic alcohols in a Heck reaction with tandem isomerization to selectively afford high yields of 1,5-diarylalkan-1-ones has been developed. Mechanistic insight was gained through NMR studies of products derived from deuterium-labeled intermediates.Entities:
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Year: 2009 PMID： 19209924 DOI： 10.1021/ol900036y
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005