Literature DB >> 19205073

Regression analysis of mean quality-adjusted survival time based on pseudo-observations.

G Tunes-da-Silva1, J P Klein.   

Abstract

Regression models for the mean quality-adjusted survival time are specified from hazard functions of transitions between two states and the mean quality-adjusted survival time may be a complex function of covariates. We discuss a regression model for the mean quality-adjusted survival (QAS) time based on pseudo-observations, which has the advantage of directly modeling the effect of covariates in the QAS time. Both Monte Carlo simulations and a real data set are studied. Copyright (c) 2009 John Wiley & Sons, Ltd.

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Year:  2009        PMID: 19205073      PMCID: PMC2715957          DOI: 10.1002/sim.3529

Source DB:  PubMed          Journal:  Stat Med        ISSN: 0277-6715            Impact factor:   2.373


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