Literature DB >> 19201798

The Mycobacterium tuberculosis GroEL1 chaperone is a substrate of Ser/Thr protein kinases.

Marc J Canova1, Laurent Kremer, Virginie Molle.   

Abstract

We demonstrate that Mycobacterium tuberculosis GroEL1 is phosphorylated by PknF at two positions, Thr25 and Thr54. Unexpectedly, Mycobacterium smegmatis GroEL1 is not a substrate of its cognate PknF. This study shows that the phosphorylation profiles of conserved proteins are species dependent and provide insights that may explain the numerous biological functions of these important proteins.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 19201798      PMCID： PMC2668390          DOI： 10.1128/JB.01569-08

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  36 in total

Review 1.  The conformational plasticity of protein kinases.

Authors:  Morgan Huse; John Kuriyan
Journal:  Cell       Date:  2002-05-03       Impact factor: 41.582

2.  An FHA phosphoprotein recognition domain mediates protein EmbR phosphorylation by PknH, a Ser/Thr protein kinase from Mycobacterium tuberculosis.

Authors:  Virginie Molle; Laurent Kremer; Christine Girard-Blanc; Gurdyal S Besra; Alain J Cozzone; Jean-François Prost
Journal:  Biochemistry       Date:  2003-12-30       Impact factor: 3.162

3.  Protein PknE, a novel transmembrane eukaryotic-like serine/threonine kinase from Mycobacterium tuberculosis.

Authors:  Virginie Molle; Christine Girard-Blanc; Laurent Kremer; Patricia Doublet; Alain J Cozzone; Jean-François Prost
Journal:  Biochem Biophys Res Commun       Date:  2003-09-05       Impact factor: 3.575

4.  pETPhos: a customized expression vector designed for further characterization of Ser/Thr/Tyr protein kinases and their substrates.

Authors:  Marc J Canova; Laurent Kremer; Virginie Molle
Journal:  Plasmid       Date:  2008-07-01       Impact factor: 3.466

Review 5.  Microbial molecular chaperones.

Authors:  P A Lund
Journal:  Adv Microb Physiol       Date:  2001       Impact factor: 3.517

Review 6.  The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis.

Authors:  Y Av-Gay; M Everett
Journal:  Trends Microbiol       Date:  2000-05       Impact factor: 17.079

7.  Mycobacterium tuberculosis chaperonin 60.1 is a more potent cytokine stimulator than chaperonin 60.2 (Hsp 65) and contains a CD14-binding domain.

Authors:  J C Lewthwaite; A R Coates; P Tormay; M Singh; P Mascagni; S Poole; M Roberts; L Sharp; B Henderson
Journal:  Infect Immun       Date:  2001-12       Impact factor: 3.441

8.  Dissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays.

Authors:  Graham R Stewart; Lorenz Wernisch; Richard Stabler; Joseph A Mangan; Jason Hinds; Ken G Laing; Douglas B Young; Philip D Butcher
Journal:  Microbiology       Date:  2002-10       Impact factor: 2.777

9.  Mycobacteriophage Bxb1 integrates into the Mycobacterium smegmatis groEL1 gene.

Authors:  Amy I Kim; Pallavi Ghosh; Michelle A Aaron; Lori A Bibb; Shruti Jain; Graham F Hatfull
Journal:  Mol Microbiol       Date:  2003-10       Impact factor: 3.501

10.  PknB kinase activity is regulated by phosphorylation in two Thr residues and dephosphorylation by PstP, the cognate phospho-Ser/Thr phosphatase, in Mycobacterium tuberculosis.

Authors:  Brigitte Boitel; Miguel Ortiz-Lombardía; Rosario Durán; Fréderique Pompeo; Stewart T Cole; Carlos Cerveñansky; Pedro M Alzari
Journal:  Mol Microbiol       Date:  2003-09       Impact factor: 3.501
View more
  21 in total

1.  Identification of multiple substrates of the StkP Ser/Thr protein kinase in Streptococcus pneumoniae.

Authors:  Linda Nováková; Silvia Bezousková; Petr Pompach; Petra Spidlová; Lenka Sasková; Jaroslav Weiser; Pavel Branny
Journal:  J Bacteriol       Date:  2010-05-07       Impact factor: 3.490

2.  Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis.

Authors:  Romain Veyron-Churlet; Isabelle Zanella-Cléon; Martin Cohen-Gonsaud; Virginie Molle; Laurent Kremer
Journal:  J Biol Chem       Date:  2010-02-23       Impact factor: 5.157

3.  Key residues in Mycobacterium tuberculosis protein kinase G play a role in regulating kinase activity and survival in the host.

Authors:  Divya Tiwari; Rajnish Kumar Singh; Kasturi Goswami; Sunil Kumar Verma; Balaji Prakash; Vinay Kumar Nandicoori
Journal:  J Biol Chem       Date:  2009-07-28       Impact factor: 5.157

Review 4.  Eukaryote-like serine/threonine kinases and phosphatases in bacteria.

Authors:  Sandro F F Pereira; Lindsie Goss; Jonathan Dworkin
Journal:  Microbiol Mol Biol Rev       Date:  2011-03       Impact factor: 11.056

5.  Phosphorylation of mycobacterial PcaA inhibits mycolic acid cyclopropanation: consequences for intracellular survival and for phagosome maturation block.

Authors:  Rosa Milagros Corrales; Virginie Molle; Jade Leiba; Lionel Mourey; Chantal de Chastellier; Laurent Kremer
Journal:  J Biol Chem       Date:  2012-05-23       Impact factor: 5.157

6.  Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms.

Authors:  Anil K Ojha; Xavier Trivelli; Yann Guerardel; Laurent Kremer; Graham F Hatfull
Journal:  J Biol Chem       Date:  2010-04-07       Impact factor: 5.157

7.  Phosphorylation of enoyl-acyl carrier protein reductase InhA impacts mycobacterial growth and survival.

Authors:  Shazia Khan; Sathya Narayanan Nagarajan; Amit Parikh; Sharmishtha Samantaray; Albel Singh; Devanand Kumar; Rajendra P Roy; Apoorva Bhatt; Vinay Kumar Nandicoori
Journal:  J Biol Chem       Date:  2010-09-23       Impact factor: 5.157

8.  Interaction of Mycobacterium tuberculosis elongation factor Tu with GTP is regulated by phosphorylation.

Authors:  Andaleeb Sajid; Gunjan Arora; Meetu Gupta; Anshika Singhal; Kausik Chakraborty; Vinay Kumar Nandicoori; Yogendra Singh
Journal:  J Bacteriol       Date:  2011-07-29       Impact factor: 3.490

9.  Understanding the role of PknJ in Mycobacterium tuberculosis: biochemical characterization and identification of novel substrate pyruvate kinase A.

Authors:  Gunjan Arora; Andaleeb Sajid; Meetu Gupta; Asani Bhaduri; Pawan Kumar; Sharmila Basu-Modak; Yogendra Singh
Journal:  PLoS One       Date:  2010-05-24       Impact factor: 3.240

10.  The Mycobacterium tuberculosis Ser/Thr kinase substrate Rv2175c is a DNA-binding protein regulated by phosphorylation.

Authors:  Martin Cohen-Gonsaud; Philippe Barthe; Marc J Canova; Charlotte Stagier-Simon; Laurent Kremer; Christian Roumestand; Virginie Molle
Journal:  J Biol Chem       Date:  2009-05-20       Impact factor: 5.157
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.