| Literature DB >> 19199669 |
Praew Thansandote1, Christina Gouliaras, Marc-Olivier Turcotte-Savard, Mark Lautens.
Abstract
A palladium-catalyzed domino ortho-alkylation/alkenylation forming up to three new C-C bonds furnishes functionalized tetrahydroisoquinolines in up to 87% yield. Extension to the formation of tetrahydrobenzoazepines and tetrahydroisoquinolinones is presented.Entities:
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Year: 2009 PMID： 19199669 DOI： 10.1021/jo8025725
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354