Literature DB >> 19199652

Biomedical application of orexin/hypocretin receptor ligands in neuroscience.

Christoph Boss1, Catherine Brisbare-Roch, Francois Jenck.   

Abstract

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Year:  2009        PMID： 19199652     DOI： 10.1021/jm801296d

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  17 in total

Review 1.  Chemistry and biology of multicomponent reactions.

Authors:  Alexander Dömling; Wei Wang; Kan Wang
Journal:  Chem Rev       Date:  2012-03-22       Impact factor: 60.622

Review 2.  Orexin receptors: pharmacology and therapeutic opportunities.

Authors:  Thomas E Scammell; Christopher J Winrow
Journal:  Annu Rev Pharmacol Toxicol       Date:  2011       Impact factor: 13.820

3.  Effect of 1-substitution on tetrahydroisoquinolines as selective antagonists for the orexin-1 receptor.

Authors:  David A Perrey; Nadezhda A German; Ann M Decker; David Thorn; Jun-Xu Li; Brian P Gilmour; Brian F Thomas; Danni L Harris; Scott P Runyon; Yanan Zhang
Journal:  ACS Chem Neurosci       Date:  2015-02-12       Impact factor: 4.418

4.  Synthesis and Evaluation of Orexin-1 Receptor Antagonists with Improved Solubility and CNS Permeability.

Authors:  David A Perrey; Ann M Decker; Yanan Zhang
Journal:  ACS Chem Neurosci       Date:  2017-11-20       Impact factor: 4.418

5.  Disubstituted piperidines as potent orexin (hypocretin) receptor antagonists.

Authors:  Rong Jiang; Xinyi Song; Purva Bali; Anthony Smith; Claudia Ruiz Bayona; Li Lin; Michael D Cameron; Patricia H McDonald; Paul J Kenny; Theodore M Kamenecka
Journal:  Bioorg Med Chem Lett       Date:  2012-05-04       Impact factor: 2.823

6.  Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beads.

Authors:  Xin Qi; John Astle; Thomas Kodadek
Journal:  Mol Biosyst       Date:  2009-09-29

Review 7.  The orexin receptor OX(1)R in colon cancer: a promising therapeutic target and a new paradigm in G protein-coupled receptor signalling through ITIMs.

Authors:  Marc Laburthe; Thierry Voisin
Journal:  Br J Pharmacol       Date:  2012-03       Impact factor: 8.739

Review 8.  Therapeutics development for addiction: Orexin-1 receptor antagonists.

Authors:  David A Perrey; Yanan Zhang
Journal:  Brain Res       Date:  2018-08-24       Impact factor: 3.252

9.  Truncated Orexin Peptides: Structure-Activity Relationship Studies.

Authors:  Nadezhda A German; Ann M Decker; Brian P Gilmour; Brian F Thomas; Yanan Zhang
Journal:  ACS Med Chem Lett       Date:  2013-12-12       Impact factor: 4.345

10.  Substituted tetrahydroisoquinolines as selective antagonists for the orexin 1 receptor.

Authors:  David A Perrey; Nadezhda A German; Brian P Gilmour; Jun-Xu Li; Danni L Harris; Brian F Thomas; Yanan Zhang
Journal:  J Med Chem       Date:  2013-08-26       Impact factor: 7.446
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