Literature DB >> 19199109

Finite element predictions compared to experimental results for the effective modulus of bone tissue engineering scaffolds fabricated by selective laser sintering.

S Cahill1, S Lohfeld, P E McHugh.   

Abstract

A current challenge in bone tissue engineering is to create scaffolds with suitable mechanical properties, high porosity, full interconnectivity and suitable pore size. In this paper, polyamide and polycaprolactone scaffolds were fabricated using a solid free form technique known as selective laser sintering. These scaffolds had fully interconnected pores, minimized strut thickness, and a porosity of approximately 55%. Tensile and compression tests as well as finite element analysis were carried out on these scaffolds. It was found that the values predicted for the effective modulus by the FE model were much higher than the actual values obtained from experimental results. One possible explanation for this discrepancy, viz. the surface roughness of the scaffold and the presence of micropores in the scaffold struts, was investigated with a view to making recommendations on improving FE model configurations for accurate effective property predictions.

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Year:  2009        PMID: 19199109     DOI: 10.1007/s10856-009-3693-5

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN: 0957-4530            Impact factor:   3.896


  8 in total

1.  Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling.

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Journal:  J Biomed Mater Res       Date:  2001-05

Review 2.  Functional tissue engineering: the role of biomechanics.

Authors:  D L Butler; S A Goldstein; F Guilak
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3.  Engineering bone regeneration with bioabsorbable scaffolds with novel microarchitecture.

Authors:  K Whang; K E Healy; D R Elenz; E K Nam; D C Tsai; C H Thomas; G W Nuber; F H Glorieux; R Travers; S M Sprague
Journal:  Tissue Eng       Date:  1999-02

4.  Scaffolds in tissue engineering bone and cartilage.

Authors:  D W Hutmacher
Journal:  Biomaterials       Date:  2000-12       Impact factor: 12.479

5.  Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints.

Authors:  S J Hollister; R D Maddox; J M Taboas
Journal:  Biomaterials       Date:  2002-10       Impact factor: 12.479

Review 6.  Bone tissue engineering: state of the art and future trends.

Authors:  António J Salgado; Olga P Coutinho; Rui L Reis
Journal:  Macromol Biosci       Date:  2004-08-09       Impact factor: 4.979

7.  Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering.

Authors:  Jessica M Williams; Adebisi Adewunmi; Rachel M Schek; Colleen L Flanagan; Paul H Krebsbach; Stephen E Feinberg; Scott J Hollister; Suman Das
Journal:  Biomaterials       Date:  2005-01-23       Impact factor: 12.479

8.  Engineering craniofacial scaffolds.

Authors:  S J Hollister; C Y Lin; E Saito; C Y Lin; R D Schek; J M Taboas; J M Williams; B Partee; C L Flanagan; A Diggs; E N Wilke; G H Van Lenthe; R Müller; T Wirtz; S Das; S E Feinberg; P H Krebsbach
Journal:  Orthod Craniofac Res       Date:  2005-08       Impact factor: 1.826

  8 in total
  10 in total

1.  An approach to architecture 3D scaffold with interconnective microchannel networks inducing angiogenesis for tissue engineering.

Authors:  Jiaoxia Sun; Yuanliang Wang; Zhiyong Qian; Chenbo Hu
Journal:  J Mater Sci Mater Med       Date:  2011-08-23       Impact factor: 3.896

2.  Improving the finite element model accuracy of tissue engineering scaffolds produced by selective laser sintering.

Authors:  S Lohfeld; S Cahill; H Doyle; P E McHugh
Journal:  J Mater Sci Mater Med       Date:  2015-01-13       Impact factor: 3.896

Review 3.  Selective laser sintering in biomedical engineering.

Authors:  Alida Mazzoli
Journal:  Med Biol Eng Comput       Date:  2012-12-19       Impact factor: 2.602

4.  Mechanical and microstructural properties of polycaprolactone scaffolds with one-dimensional, two-dimensional, and three-dimensional orthogonally oriented porous architectures produced by selective laser sintering.

Authors:  Shaun Eshraghi; Suman Das
Journal:  Acta Biomater       Date:  2010-02-08       Impact factor: 8.947

5.  Micromechanical finite-element modeling and experimental characterization of the compressive mechanical properties of polycaprolactone-hydroxyapatite composite scaffolds prepared by selective laser sintering for bone tissue engineering.

Authors:  Shaun Eshraghi; Suman Das
Journal:  Acta Biomater       Date:  2012-04-19       Impact factor: 8.947

6.  In situ 4D tomography image analysis framework to follow sintering within 3D-printed glass scaffolds.

Authors:  Achintha I Kondarage; Gowsihan Poologasundarampillai; Amy Nommeots-Nomm; Peter D Lee; Thilina D Lalitharatne; Nuwan D Nanayakkara; Julian R Jones; Angelo Karunaratne
Journal:  J Am Ceram Soc       Date:  2021-11-03       Impact factor: 4.186

7.  Fabrication and biocompatibility of nano non-stoichiometric apatite and poly(epsilon-caprolactone) composite scaffold by using prototyping controlled process.

Authors:  Liang Ye; Xinchen Zeng; Haojiang Li; Yi Ai
Journal:  J Mater Sci Mater Med       Date:  2009-09-27       Impact factor: 3.896

8.  Scaffold library for tissue engineering: a geometric evaluation.

Authors:  Nattapon Chantarapanich; Puttisak Puttawibul; Sedthawatt Sucharitpwatskul; Pongnarin Jeamwatthanachai; Samroeng Inglam; Kriskrai Sitthiseripratip
Journal:  Comput Math Methods Med       Date:  2012-09-26       Impact factor: 2.238

Review 9.  Advances and prospects in biomimetic multilayered scaffolds for articular cartilage regeneration.

Authors:  Liwei Fu; Zhen Yang; Cangjian Gao; Hao Li; Zhiguo Yuan; Fuxin Wang; Xiang Sui; Shuyun Liu; Quanyi Guo
Journal:  Regen Biomater       Date:  2020-09-30

10.  Selective Laser Sintering of PA 2200 for Hip Implant Applications: Finite Element Analysis, Process Optimization, Morphological and Mechanical Characterization.

Authors:  Răzvan Păcurar; Petru Berce; Anna Petrilak; Ovidiu Nemeş; Cristina Ştefana Miron Borzan; Marta Harničárová; Ancuţa Păcurar
Journal:  Materials (Basel)       Date:  2021-07-29       Impact factor: 3.623

  10 in total

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