Literature DB >> 1919592

Additional bioactive heptenes from Melodorum fruticosum.

J H Jung1, C J Chang, D L Smith, J L McLaughlin, S Pummangura, C Chaichantipyuth, C Patarapanich.   

Abstract

Four additional new bioactive heptenes, melodorinol [2], homomelodienone [4], 7-hydroxy-6-hydromelodienone [5], and homoisomelodienone [7] have been isolated from Melodorum fruticosum. These compounds were slightly to significantly cytotoxic to human tumor cell lines. Their structures have been determined by comparison of their 1H-nmr, 13C-nmr, and mass spectral data with those of prototype compounds (acetylmelodorinol [1], melodienone 3, and isomelodienone [6]).

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Year:  1991        PMID: 1919592     DOI: 10.1021/np50074a023

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  6 in total

1.  Antiproliferative compounds of Artabotrys madagascariensis from the Madagascar rainforest.

Authors:  Brian T Murphy; Shugeng Cao; Peggy J Brodie; James S Miller; Fidy Ratovoson; Chris Birkinshaw; Etienne Rakotobe; Vincent E Rasamison; Karen Tendyke; Edward M Suh; David G I Kingston
Journal:  Nat Prod Res       Date:  2008       Impact factor: 2.861

2.  Inhibition of Pro-Inflammatory Functions of Human Neutrophils by Constituents of Melodorum fruticosum Leaves.

Authors:  Nora S Engels; Birgit Waltenberger; Barbara Michalak; Loi Huynh; Hung Tran; Anna K Kiss; Hermann Stuppner
Journal:  Chem Biodivers       Date:  2018-11-15       Impact factor: 2.408

3.  Melodamide A from Melodorum fruticosum - Quantification using HPLC and one-step-isolation by centrifugal partition chromatography.

Authors:  Nora S Engels; Birgit Waltenberger; Stefan Schwaiger; Loi Huynh; Hung Tran; Hermann Stuppner
Journal:  J Sep Sci       Date:  2019-08-08       Impact factor: 3.645

4.  New Flavonoid Derivatives from Melodorum fruticosum and Their α-Glucosidase Inhibitory and Cytotoxic Activities.

Authors:  Lien T M Do; Jirapast Sichaem
Journal:  Molecules       Date:  2022-06-22       Impact factor: 4.927

5.  A Meroisoprenoid, Heptenolides, and C-Benzylated Flavonoids from Sphaerocoryne gracilis ssp. gracilis.

Authors:  Gasper Maeda; Joan J E Munissi; Sofia Lindblad; Sandra Duffy; Jerry Pelletier; Vicky M Avery; Stephen S Nyandoro; Máté Erdélyi
Journal:  J Nat Prod       Date:  2020-02-18       Impact factor: 4.050

6.  An improved dental composite with potent antibacterial function.

Authors:  Rashed Almousa; Xin Wen; Gregory G Anderson; Dong Xie
Journal:  Saudi Dent J       Date:  2019-03-26
  6 in total

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