| Literature DB >> 19194013 |
Takao Hibi1, Hiromi Yamamoto, Genichi Nakamura, Hiroshi Takagi.
Abstract
Mpr1 is an enzyme that catalyzes the N-acetylation of the toxic L-azetidine-2-carboxylic acid (AZC). Recently, Mpr1 has been shown to reduce levels of intracellular reactive oxygen species (ROS) under oxidative stress. The natural substrate involved in the ROS elimination in vivo is still unknown. Mpr1 has been purified and crystallized in space groups P1 and P3(1)12. X-ray data were collected to 1.9 A resolution from a trigonal crystal soaked with AZC.Entities:
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Year: 2009 PMID: 19194013 PMCID: PMC2635863 DOI: 10.1107/S1744309109000153
Source DB: PubMed Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun ISSN: 1744-3091