Literature DB >> 19192678

A MCMC method for resolving two person mixtures.

James M Curran1.   

Abstract

In this paper a Monte Carlo Markov Chain (MCMC) method for resolving DNA mixtures containing at most four peaks per locus into a major and a minor contributor is presented. Unlike previous methods, this method can provide posterior probability assessments of the most probable genotype and a likely range for the mixing proportion. The proposed method is applied to two DNA mixtures where the true genotypes of the contributors are known. The method provides posterior probabilities of the genotypes of the contributes which concord strongly with the known facts.

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Year:  2008        PMID: 19192678     DOI: 10.1016/j.scijus.2007.09.014

Source DB:  PubMed          Journal:  Sci Justice        ISSN: 1355-0306            Impact factor:   2.124


  6 in total

Review 1.  Separation/extraction, detection, and interpretation of DNA mixtures in forensic science (review).

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Journal:  Int J Legal Med       Date:  2018-05-25       Impact factor: 2.686

2.  An information gap in DNA evidence interpretation.

Authors:  Mark W Perlin; Alexander Sinelnikov
Journal:  PLoS One       Date:  2009-12-16       Impact factor: 3.240

Review 3.  The National DNA Data Bank of Canada: a Quebecer perspective.

Authors:  Emmanuel Milot; Marie M J Lecomte; Hugo Germain; Frank Crispino
Journal:  Front Genet       Date:  2013-11-20       Impact factor: 4.599

4.  TrueAllele casework on Virginia DNA mixture evidence: computer and manual interpretation in 72 reported criminal cases.

Authors:  Mark W Perlin; Kiersten Dormer; Jennifer Hornyak; Lisa Schiermeier-Wood; Susan Greenspoon
Journal:  PLoS One       Date:  2014-03-25       Impact factor: 3.240

5.  New York State TrueAllele ® casework validation study.

Authors:  Mark W Perlin; Jamie L Belrose; Barry W Duceman
Journal:  J Forensic Sci       Date:  2013-07-18       Impact factor: 1.832

6.  Inclusion probability for DNA mixtures is a subjective one-sided match statistic unrelated to identification information.

Authors:  Mark William Perlin
Journal:  J Pathol Inform       Date:  2015-10-28
  6 in total

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